Arzu Ferhatosmanoğlu, Leyla Baykal Selçuk, İbrahim Etem Arıca
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引用次数: 0
Abstract
Purpose
Scabies is a common parasitic skin condition with significant morbidity. This study aimed to identify risk factors for treatment failure and analyze lesion distribution patterns in relation to sex, age, and comorbidities in patients with treatment-resistant scabies.
Methods
The study included patients with dermatologist-confirmed scabies who had received at least one treatment within the past six months without clinical improvement. Clinical, sociodemographic, and cutaneous findings were evaluated.
Results
A total of 246 patients were included (130 females, 52.8%; 116 males, 47.2%). Males had significantly higher rates of excoriation (p < 0.001), pustules (p = 0.047), tunnels (p = 0.046), and genital involvement (p = 0.012). Nodules were more common in individuals under 18 (p = 0.003), while excoriations predominated in those over 65 (p < 0.001). Longer pruritus duration was observed in older adults, rural residents, and patients receiving weekend home visits (p = 0.017, p < 0.001, and p = 0.011, respectively), and was associated with increased lesion severity. A threefold increase in abdominal involvement and a 3.33-fold increase in pustules were seen in patients receiving three or more treatments. Higher education (university or above) was linked to a 46% reduced risk of treatment-resistant scabies.
Conclusions
This study identifies key demographic and clinical risk factors associated with treatment failure in scabies and underscores the need for targeted management strategies. To the best of our knowledge, it is the first to comprehensively investigate lesion distribution and clinical patterns of resistant scabies in relation to sex, age, and comorbid conditions.
期刊介绍:
Acta Parasitologica is an international journal covering the latest advances in the subject.
Acta Parasitologica publishes original papers on all aspects of parasitology and host-parasite relationships, including the latest discoveries in biochemical and molecular biology of parasites, their physiology, morphology, taxonomy and ecology, as well as original research papers on immunology, pathology, and epidemiology of parasitic diseases in the context of medical, veterinary and biological sciences. The journal also publishes short research notes, invited review articles, book reviews.
The journal was founded in 1953 as "Acta Parasitologica Polonica" by the Polish Parasitological Society and since 1954 has been published by W. Stefanski Institute of Parasitology of the Polish Academy of Sciences in Warsaw. Since 1992 in has appeared as Acta Parasitologica in four issues per year.