Recent approaches in green liquid chromatography for pharmaceutical analysis: A comprehensive review on green analytical sustainable chemistry

Sustainable Chemistry One World Pub Date : 2025-05-23 DOI:10.1016/j.scowo.2025.100069

Sachin D. Patil , Shreya R. Karode , Neha R. Kolate , Tanay M. Korde

{"title":"Recent approaches in green liquid chromatography for pharmaceutical analysis: A comprehensive review on green analytical sustainable chemistry","authors":"Sachin D. Patil , Shreya R. Karode , Neha R. Kolate , Tanay M. Korde","doi":"10.1016/j.scowo.2025.100069","DOIUrl":null,"url":null,"abstract":"<div><div>In today's society, green chemistry has become crucial, and researchers are working towards sustainable development. Green analytical chemistry (GAC) is currently beginning to utilize eco-friendly methods. This results in a large number of green liquid chromatographic (LC) analyses of medications in various dosage forms.</div><div>Pharmaceutical High Performance Liquid Chromatography (HPLC) analysis has been used to discuss greenness or eco-friendly tools such as the Green Analytic Procedure Index (GAPI), National Environmental Methods Index (NEMI), analytical eco-scale assessment (ESA), analytical method greenness score (AMGS), and analytical greenness matric approach (AGREE). This study explores innovative green analytical chemistry methods, minimizing environmental impact while maintaining analytical performance. This review includes various article that has been published in the field of pharmaceutical green HPLC analysis. In order to promote sustainable analytical techniques, we also illustrated the idea of circular analytical chemistry (CAC) and its twelve guiding principles. We investigated developed and validated sustainable protocols using eco-friendly solvents, micro extraction techniques, and energy-efficient instrumentation. The results demonstrated significant reductions in waste, energy consumption, and the use of toxic reagents. This approach paves the way for environmentally responsible chemical analysis.</div></div>","PeriodicalId":101197,"journal":{"name":"Sustainable Chemistry One World","volume":"6 ","pages":"Article 100069"},"PeriodicalIF":0.0000,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sustainable Chemistry One World","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2950357425000265","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

In today's society, green chemistry has become crucial, and researchers are working towards sustainable development. Green analytical chemistry (GAC) is currently beginning to utilize eco-friendly methods. This results in a large number of green liquid chromatographic (LC) analyses of medications in various dosage forms.

Pharmaceutical High Performance Liquid Chromatography (HPLC) analysis has been used to discuss greenness or eco-friendly tools such as the Green Analytic Procedure Index (GAPI), National Environmental Methods Index (NEMI), analytical eco-scale assessment (ESA), analytical method greenness score (AMGS), and analytical greenness matric approach (AGREE). This study explores innovative green analytical chemistry methods, minimizing environmental impact while maintaining analytical performance. This review includes various article that has been published in the field of pharmaceutical green HPLC analysis. In order to promote sustainable analytical techniques, we also illustrated the idea of circular analytical chemistry (CAC) and its twelve guiding principles. We investigated developed and validated sustainable protocols using eco-friendly solvents, micro extraction techniques, and energy-efficient instrumentation. The results demonstrated significant reductions in waste, energy consumption, and the use of toxic reagents. This approach paves the way for environmentally responsible chemical analysis.

查看原文本刊更多论文

绿色液相色谱在药物分析中的最新进展：绿色分析可持续化学综述

在当今社会，绿色化学已经变得至关重要，研究人员正在朝着可持续发展的方向努力。绿色分析化学（GAC）目前开始采用环保的方法。这导致大量的绿色液相色谱（LC）分析在各种剂型的药物。药物高效液相色谱（HPLC）分析已被用于讨论绿色或环保工具，如绿色分析程序指数（GAPI）、国家环境方法指数（NEMI）、分析生态尺度评估（ESA）、分析方法绿色评分（AMGS）和分析绿色矩阵方法（AGREE）。本研究探索创新的绿色分析化学方法，在保持分析性能的同时尽量减少对环境的影响。本文综述了国内外在绿色高效液相色谱分析领域已发表的文章。为了促进可持续分析技术，我们还阐述了循环分析化学（CAC）的思想及其12条指导原则。我们研究开发并验证了使用环保溶剂、微萃取技术和节能仪器的可持续方案。结果表明，废物、能源消耗和有毒试剂的使用显著减少。这种方法为对环境负责的化学分析铺平了道路。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Sustainable Chemistry One World

自引率

0.00%

发文量