Dysplastic lesions of the liver: two cases demonstrating the key pathological principles

Abstract

Two cases of steatohepatitis-associated cirrhosis containing high grade dysplastic nodules are discussed, one with hepatocellular carcinoma arising within. The spectrum of dysplastic hepatocellular lesions is explored in addition to the possible diagnostic pitfalls and strategies that may be deployed by the pathologist, particularly when differentiating malignancy from non-malignant lesions.