{"title":"Arboviruses: the hidden danger of the tropics","authors":"Zhen Yun Siew, Isaac Seow, Xin Rui Lim, Chen Zhe Tang, Fadhilah Moh Djamil, Ghee Khang Ong, Pooi Pooi Leong, Siew Tung Wong, Kenny Voon","doi":"10.1007/s00705-025-06314-5","DOIUrl":null,"url":null,"abstract":"<div><p>Arboviruses are viruses that are transmitted by arthropods such as mosquitoes, ticks, and flies, and most of them are RNA viruses. Vector-borne transmission occurs when an infected arthropod bites a vertebrate host, allowing the virus to enter the bloodstream and initiate infection. Arboviruses are known to cause significant morbidity and mortality in mammals, and at least a hundred of them have been identified as human pathogens. In this review, we provide an updated overview of four prominent arboviruses that are present in Southeast Asia (SEA): dengue virus (DENV), Japanese encephalitis virus (JEV), Zika virus (ZIKV), and chikungunya virus (CHIKV). The epidemiology and pathogenesis of these viruses and the currently used methods for diagnosis, prevention, and treatment of arbovirus infections are discussed in detail. Finally, we summarise the concerns and future considerations for combating these dangerous pathogens.</p></div>","PeriodicalId":8359,"journal":{"name":"Archives of Virology","volume":"170 7","pages":""},"PeriodicalIF":2.5000,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Virology","FirstCategoryId":"3","ListUrlMain":"https://link.springer.com/article/10.1007/s00705-025-06314-5","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VIROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Arboviruses are viruses that are transmitted by arthropods such as mosquitoes, ticks, and flies, and most of them are RNA viruses. Vector-borne transmission occurs when an infected arthropod bites a vertebrate host, allowing the virus to enter the bloodstream and initiate infection. Arboviruses are known to cause significant morbidity and mortality in mammals, and at least a hundred of them have been identified as human pathogens. In this review, we provide an updated overview of four prominent arboviruses that are present in Southeast Asia (SEA): dengue virus (DENV), Japanese encephalitis virus (JEV), Zika virus (ZIKV), and chikungunya virus (CHIKV). The epidemiology and pathogenesis of these viruses and the currently used methods for diagnosis, prevention, and treatment of arbovirus infections are discussed in detail. Finally, we summarise the concerns and future considerations for combating these dangerous pathogens.
期刊介绍：
Archives of Virology publishes original contributions from all branches of research on viruses, virus-like agents, and virus infections of humans, animals, plants, insects, and bacteria. Coverage spans a broad spectrum of topics, from descriptions of newly discovered viruses, to studies of virus structure, composition, and genetics, to studies of virus interactions with host cells, organisms and populations. Studies employ molecular biologic, molecular genetics, and current immunologic and epidemiologic approaches. Contents include studies on the molecular pathogenesis, pathophysiology, and genetics of virus infections in individual hosts, and studies on the molecular epidemiology of virus infections in populations. Also included are studies involving applied research such as diagnostic technology development, monoclonal antibody panel development, vaccine development, and antiviral drug development.Archives of Virology wishes to publish obituaries of recently deceased well-known virologists and leading figures in virology.
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