Maria Grazia Carnevale , Riccardo Ray Colciago , Maria Carmen De Santis , Laura Cortesi , Cinzia De Marco , Antonio Marra , Andrea Vingiani , Franco Nolè , Giuseppe Curigliano , Giancarlo Pruneri , Antonio Llombart-Cussac , Serena Di Cosimo , Javier Cortes
{"title":"Advancing breast cancer therapy in the era of molecular diagnostics","authors":"Maria Grazia Carnevale , Riccardo Ray Colciago , Maria Carmen De Santis , Laura Cortesi , Cinzia De Marco , Antonio Marra , Andrea Vingiani , Franco Nolè , Giuseppe Curigliano , Giancarlo Pruneri , Antonio Llombart-Cussac , Serena Di Cosimo , Javier Cortes","doi":"10.1016/j.breast.2025.104488","DOIUrl":null,"url":null,"abstract":"<div><div>Advances in cancer biology and drug development now enable treatments tailored to individual tumor profile. Targeting specific molecular alterations marked a significant step forward in cancer care, including breast cancer. Access to these therapies is improving thanks to the implementation of molecular tumor boards and efforts to provide molecular diagnostics at sustainable costs for all. In this context, we highlight recent progress in breast cancer therapy, focusing on biomarker-driven approaches, immunotherapy, and precision medicine paving the way for increasingly personalized and effective options.</div></div>","PeriodicalId":9093,"journal":{"name":"Breast","volume":"82 ","pages":"Article 104488"},"PeriodicalIF":5.7000,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Breast","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0960977625005053","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Advances in cancer biology and drug development now enable treatments tailored to individual tumor profile. Targeting specific molecular alterations marked a significant step forward in cancer care, including breast cancer. Access to these therapies is improving thanks to the implementation of molecular tumor boards and efforts to provide molecular diagnostics at sustainable costs for all. In this context, we highlight recent progress in breast cancer therapy, focusing on biomarker-driven approaches, immunotherapy, and precision medicine paving the way for increasingly personalized and effective options.
期刊介绍:
The Breast is an international, multidisciplinary journal for researchers and clinicians, which focuses on translational and clinical research for the advancement of breast cancer prevention, diagnosis and treatment of all stages.