Current Use, Effectiveness, and Safety of Image-Guided Bone Biopsies: Insights from the Registry of the German Society for Interventional Radiology and Minimally Invasive Therapy (DeGIR) Data 2018-2022.

IF 1.3 4区医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Rofo-fortschritte Auf Dem Gebiet Der Rontgenstrahlen Und Der Bildgebenden Verfahren Pub Date : 2025-05-23 DOI:10.1055/a-2600-3915

Sebastian Zensen, Marcel Klaus Opitz, Florian Behr, Yan Li, Johannes Haubold, Mathias Holtkamp, Luca Salhöfer, Denise Bos, Michael Moche, Michael Forsting, Benedikt Schaarschmidt

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Abstract

Image-guided bone biopsies have become indispensable in the diagnosis of a wide range of diseases, from incidental suspicious lesions to the evaluation of treatment response and the staging of malignancies. The aim of this evaluation of the prospectively managed voluntary multinational registry of the German Society for Interventional Radiology and Minimally Invasive Therapy (DeGIR) was to analyze the use, technical success, and complications of image-guided diagnostic biopsies of bone lesions.All bone biopsies reported in the DeGIR registry between 2018 and 2022 were included. Technical success was defined as the successful image-guided placement of the sampling device within the bone lesion. Technical success and complication rates were compared across various parameters by Fisher's exact and chi-square test. p<0.05 was considered statistically significant.A total of 17397 diagnostic punctures (female: 52% (9046/17397), outpatient procedures: 34% (5924/17397), median age: 64y (IQR 51-75y)) from 214 centers in Germany, Austria, and Switzerland were analyzed. The technical success rate was 98.9% (17201/17397), with histological representativeness in 93.2% of cases (10316/11071). Outpatient procedures had a higher technical success rate (99.3%, 5884/5924) compared to inpatient procedures (98.6%, 11316/11473, p<0.0001), but lower histological representativeness (91.1%, 1284/1410 vs. 93.5%, 9031/9661, p=0.001). The overall complication rate was 0.62% (108/17397), with major complications being predominantly parenchymal bleeding. Solid or subsolid lesions had higher histological representativeness (94.0%, 7846/8346) compared to necrotic-cystic lesions (90.3%, 1558/1725, p<0.0001).Image-guided bone biopsies are highly effective and safe. The high technical success rates and low complication rates underscore their clinical utility. The DeGIR registry provides valuable insight into the performance and outcomes of these procedures, highlighting their importance in interventional radiology. · Image-guided bone biopsies have a high technical success rate.. · The complication rate is generally low, with major complications being rare.. · The further reduction of complications in patients with normal coagulation parameters indicate that bone biopsies might be safely performed as outpatient procedures.. · Zensen S, Opitz MK, Behr F et al. Current Use, Effectiveness, and Safety of Image-Guided Bone Biopsies: Insight from the Registry of the German Society for Interventional Radiology and Minimally Invasive Therapy (DeGIR) Data 2018-2022. Rofo 2025; DOI 10.1055/a-2600-3915.

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图像引导骨活检的当前使用、有效性和安全性：来自德国介入放射学和微创治疗学会（DeGIR）注册数据2018-2022的见解

影像引导下的骨活检已成为广泛疾病诊断中不可或缺的一部分，从偶然的可疑病变到评估治疗反应和恶性肿瘤的分期。对德国介入放射学和微创治疗学会（DeGIR）前瞻性管理的多国自愿登记进行评估的目的是分析图像引导的骨病变诊断活检的使用、技术成功和并发症。纳入了2018年至2022年期间DeGIR登记处报告的所有骨活检。技术上的成功被定义为图像引导下取样装置在骨病变内的成功放置。通过Fisher精确检验和卡方检验比较不同参数的技术成功率和并发症发生率。p

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Rofo-fortschritte Auf Dem Gebiet Der Rontgenstrahlen Und Der Bildgebenden Verfahren 医学-核医学

CiteScore

1.20

自引率

5.60%

发文量

340

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