Alternative healthy eating index may predict a reduced odd of endometriosis: results from a case-control study.

IF 2.4 3区医学 Q2 OBSTETRICS & GYNECOLOGY

BMC Women's Health Pub Date : 2025-05-24 DOI:10.1186/s12905-025-03805-0

Seyed Mojtaba Ghoreishy, Fatemeh Sadat Hashemi Javaheri, Sakine Ghasemisedaghat, Morvarid Noormohammadi, Ghazaleh Eslamian, Seyyedeh Neda Kazemi, Bahram Rashidkhani, Robabeh Taheripanah

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引用次数: 0

Abstract

Background: Endometriosis, characterized as an inflammatory ailment, affects females during their reproductive years, leading to decreased quality of life. Despite the pivotal role of diet as a modifiable risk factor for various chronic conditions, its potential influence on endometriosis has remained inadequately explored. This research endeavor sought to scrutinize the association between dietary alternative healthy eating index, AHEI, and the likelihood of experiencing endometriosis among women in Iran.

Methods: Conducted as a hospital-centered case-control investigation, the study enlisted individuals diagnosed with endometriosis alongside healthy counterparts, confirmed by a gynecologist, between February and September 2021 in Tehran, Iran. The pattern of diet was assessed utilizing a validated Food Frequency Questionnaire (FFQ) encompassing 168 food items. Logistic regression models were employed to explore the potential connection between AHEI and the probability of endometriosis.

Results: The analysis encompassed 105 subjects with endometriosis and 208 individuals in good health. After adjustment for total calories intake (Kcal), occupation, smoking (yes/no), age at menarche (years), menstruation duration (days), regular menstruation (yes/no), physical activity (minutes per week) and familial history of endometriosis (yes/no), it was observed that those with the high adherence to the AHEI, had about 92% lower odds of endometriosis (Odds Ratio: 0.08, 95%Confidence Intervals: 0.03, 0.24; P for trend < 0.001).

Conclusion: The investigation illustrated a protective effect of healthy eating index and its components on developing endometriosis.

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替代性健康饮食指数可预测子宫内膜异位症发生率的降低：一项病例对照研究的结果。

背景：子宫内膜异位症是一种炎症性疾病，主要影响育龄期女性，导致生活质量下降。尽管饮食作为各种慢性疾病的可改变风险因素发挥着关键作用，但其对子宫内膜异位症的潜在影响仍未得到充分探讨。本研究旨在仔细研究伊朗妇女中饮食替代健康饮食指数、AHEI和子宫内膜异位症可能性之间的关系。方法：作为一项以医院为中心的病例对照调查，该研究于2021年2月至9月在伊朗德黑兰招募了经妇科医生确认的子宫内膜异位症患者和健康患者。使用包含168种食物的有效食物频率问卷（FFQ）评估饮食模式。采用Logistic回归模型探讨AHEI与子宫内膜异位症之间的潜在联系。结果：分析包括105名子宫内膜异位症患者和208名健康个体。在调整总热量摄入（Kcal）、职业、吸烟（是/否）、初潮年龄（年）、月经持续时间（天）、月经规律（是/否）、体力活动（每周分钟）和子宫内膜异位症家族史（是/否）后，观察到那些高度遵守AHEI的人发生子宫内膜异位症的几率低约92%(优势比：0.08,95%可信范围：0.03,0.24；结论：健康饮食指数及其成分对子宫内膜异位症的发生具有保护作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Women's Health OBSTETRICS & GYNECOLOGY-

CiteScore

3.40

自引率

4.00%

发文量

444

审稿时长

>12 weeks

期刊介绍： BMC Women''s Health is an open access, peer-reviewed journal that considers articles on all aspects of the health and wellbeing of adolescent girls and women, with a particular focus on the physical, mental, and emotional health of women in developed and developing nations. The journal welcomes submissions on women''s public health issues, health behaviours, breast cancer, gynecological diseases, mental health and health promotion.