Dale O Edwick, Kerry L Burns, Lara N Buonvecchi, Xiaolu Wang, Audrey M Lim, Dale W Edgar
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引用次数: 0
Abstract
Prolonged healing time of acute burn wounds is associated with increased pain, infection, risk of scarring, poorer mobility and higher financial and emotional burden. Electrical stimulation (ES) reduces healing time in chronic wounds; however, its reported use on acute burn wounds is limited. This systematic review (SR) aimed to evaluate the relative benefit of ES compared to routine wound care on the healing time of acute burn wounds in adults. The online databases queried included Cochrane Database of SR's, MEDLINE, EMBASE, PUBMED and CINAHL. The search criteria included RCTs involving the application of ES of varying voltage, duration and modality in acute burn patients aged ≥18 years. The primary outcome investigated was days to burn wound closure, while the secondary outcomes included edema and infection. Four RCTs were discovered, involving a total of 143 participants with a mean age 35.5 years. Two RCTs demonstrated (a) 36% (2.6 days) reduction in time to wound closure with ES (p < 0.001); and (b) significant reduction in wound area with ES (11.2 ± 3.2 cm2, p < 0.001) compared to controls at 21 days. Two RCTs found ES promoted better wound-healing environments, reducing edema, bacterial infection, and biofilm. This review highlighted low-risk wound-healing benefits with ES as a feasible adjunct to routine burn care.
急性烧伤创面愈合时间延长与疼痛、感染、结疤风险增加、活动能力下降以及经济和情感负担加重有关。电刺激(ES)减少慢性伤口的愈合时间;然而,据报道其在急性烧伤伤口上的使用是有限的。本系统综述(SR)旨在评价与常规伤口护理相比,ES对成人急性烧伤创面愈合时间的相对益处。查询的在线数据库包括Cochrane Database of SR's、MEDLINE、EMBASE、PUBMED和CINAHL。检索标准包括在年龄≥18岁的急性烧伤患者中应用不同电压、持续时间和模式的ES的随机对照试验。调查的主要结果是烧伤伤口愈合的天数,而次要结果包括水肿和感染。发现了4项随机对照试验,共涉及143名参与者,平均年龄35.5岁。两项随机对照试验显示(a)使用ES可缩短36%(2.6天)的伤口愈合时间(p < 0.001);(b)与对照组相比,第21天ES组伤口面积显著减少(11.2±3.2 cm2, p < 0.001)。两项随机对照试验发现,ES促进了更好的伤口愈合环境,减少了水肿、细菌感染和生物膜。本综述强调了ES作为常规烧伤护理的一种可行辅助手段的低风险创面愈合益处。