SARS-CoV-2 infection risk by non-healthcare occupations: a systematic review and meta-analysis.

IF 2.9 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Katharina M A Gabriel, Christin Schröder, Rebecca Wolf, Ulrich Bolm-Audorff, Camilla Kienast, Joanna Smolinska, Gabriela Petereit-Haack, Andreas Seidler
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引用次数: 0

Abstract

Background: During the COVID-19 pandemic, several industries were deemed essential. However, information on infection risk in occupational settings outside of healthcare workers and medical staff (HCWs) remain scarce. Thus, a systematic review with meta-analysis was conducted to compile the risk of infection to SARS-CoV-2 in non-healthcare workers (non-HCWs).

Methods: We screened three databases (EMBASE, PubMed, medRχiv) for studies on SARS-CoV-2 infection risk in working population. Several stages of severity (infection, hospitalisation, admission to intensive care unit (ICU), mortality) were eligible. Occupational specifications were harmonised according to the German classification of professions (KldB). All reported risk estimators were considered. Studies were analysed for their risk of bias. Results of random-effects meta-analyses were assessed for their evidence according to GRADE. Subgroup analyses were run for 'outcome', 'comparison group', and 'risk of bias'.

Results: Of 9,081 publications identified, 25 were recognised as eligible, mainly describing the first year of the pandemic. For 20 occupations, we were able to carry out meta-analyses on KldB-4-level by integrating all stages of severity. Nine occupations were identified with a statistically significantly increased risk of infection for SARS-CoV-2, four of which had a relative risk (RR) of > 2: Occupations in meat processing (RR = 3.58 [95%-CI 1.46; 8.77]), occupations in building cleaning services (RR = 2.55 [95%-CI 1.51; 4.31]), occupations in cargo handling (RR = 2.52 [95%-CI 2.27; 2.79]) and cooks (RR = 2.53 [95%-CI 1.75; 3.67]). The certainty of evidence of eight results was found moderate or high.

Conclusions: The first systematic review and meta-analysis of occupational SARS-CoV-2 infection risk in occupations other than HCWs revealed a considerably elevated risk in individual related services as well as in commercial services.

Trial registration: PROSPERO CRD42021297572.

非卫生保健职业的SARS-CoV-2感染风险:系统回顾和荟萃分析
背景:在2019冠状病毒病大流行期间,有几个行业被认为是必不可少的。然而,关于卫生保健工作者和医务人员(HCWs)以外职业环境中感染风险的信息仍然很少。因此,对非卫生保健工作者(非卫生保健工作者)感染SARS-CoV-2的风险进行了系统评价和荟萃分析。方法:筛选3个数据库(EMBASE、PubMed、medRχiv)进行工作人群SARS-CoV-2感染风险的研究。严重程度的几个阶段(感染、住院、入住重症监护病房(ICU)、死亡率)符合条件。职业规范根据德国职业分类(KldB)进行协调。考虑了所有报告的风险估计。对研究进行了偏倚风险分析。随机效应荟萃分析的结果根据GRADE评估其证据。对“结果”、“对照组”和“偏倚风险”进行亚组分析。结果:在确定的9081份出版物中,有25份被认为是合格的,主要描述了大流行的第一年。对于20个职业,我们能够通过整合所有严重程度阶段对kldb -4水平进行meta分析。9个职业被确定为感染SARS-CoV-2的风险具有统计学显著性增加,其中4个职业的相对风险(RR)为bbbb2:肉类加工职业(RR = 3.58 [95%-CI 1.46;8.77]),建筑清洁服务行业(RR = 2.55[95%可信区间1.51;4.31]),货物装卸职业(RR = 2.52[95%可信区间2.27;2.79])和炊事员(RR = 2.53[95%可信区间1.75;3.67])。八个结果的证据的确定性被发现是中等或高。结论:对卫生保健工作者以外职业SARS-CoV-2感染风险的首次系统评价和荟萃分析显示,个体相关服务以及商业服务的风险显著升高。试验注册:PROSPERO CRD42021297572。
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来源期刊
Journal of Occupational Medicine and Toxicology
Journal of Occupational Medicine and Toxicology PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
6.00
自引率
0.00%
发文量
23
审稿时长
19 weeks
期刊介绍: Aimed at clinicians and researchers, the Journal of Occupational Medicine and Toxicology is a multi-disciplinary, open access journal which publishes original research on the clinical and scientific aspects of occupational and environmental health. With high-quality peer review and quick decision times, we welcome submissions on the diagnosis, prevention, management, and scientific analysis of occupational diseases, injuries, and disability. The journal also covers the promotion of health of workers, their families, and communities, and ranges from rehabilitation to tropical medicine and public health aspects.
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