{"title":"Meiosis-associated expression patterns during starvation-induced cell fusion in the protist Fisculla terrestris.","authors":"Shan Gao, Marcel Dominik Solbach, Jens Bast, Kenneth Dumack","doi":"10.1186/s12915-025-02246-3","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Unicellular eukaryotes were widely considered to r eproduce without sex. However, recent findings suggest that meiosis, and by extension (sometimes cryptic) sexual reproduction, might be present in almost all eukaryotic lineages.</p><p><strong>Results: </strong>Here, we investigate the transcriptomic response underlying starvation-induced fusion in the Rhizaria protist Fisculla terrestris. Investigations of differentially expressed genes (DEGs) with a particular focus on the expression of meiosis-associated genes suggest that some form of meiosis and recombination might occur in these Rhizaria.</p><p><strong>Conclusions: </strong>We showed that starvation triggered changes in gene expression of meiosis-associated genes in F. terrestris. However, if these processes are coupled with sexual reproduction remains to be investigated.</p>","PeriodicalId":9339,"journal":{"name":"BMC Biology","volume":"23 1","pages":"140"},"PeriodicalIF":4.4000,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12096724/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC Biology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1186/s12915-025-02246-3","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Unicellular eukaryotes were widely considered to r eproduce without sex. However, recent findings suggest that meiosis, and by extension (sometimes cryptic) sexual reproduction, might be present in almost all eukaryotic lineages.
Results: Here, we investigate the transcriptomic response underlying starvation-induced fusion in the Rhizaria protist Fisculla terrestris. Investigations of differentially expressed genes (DEGs) with a particular focus on the expression of meiosis-associated genes suggest that some form of meiosis and recombination might occur in these Rhizaria.
Conclusions: We showed that starvation triggered changes in gene expression of meiosis-associated genes in F. terrestris. However, if these processes are coupled with sexual reproduction remains to be investigated.
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