Comparative Analysis of the Effectiveness of Tranexamic Acid in Controlling Surgical Blood Loss in Patients Undergoing Liposuction.

IF 2 3区医学 Q2 SURGERY

Aesthetic Plastic Surgery Pub Date : 2025-05-22 DOI:10.1007/s00266-025-04852-6

Hüseyin Kandulu

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引用次数: 0

Abstract

Background: Liposuction is one of the most popular plastic surgeries, and blood loss is one of its major complications. Tranexamic acid (TXA), an antifibrinolytic drug, has been shown to reduce blood loss in many surgeries. In this prospective study, the effect of TXA on blood loss in patients, who underwent three different procedures including suction-assisted lipoplasty, vibrational amplification of sound energy at resonance (VASER)-assisted lipoplasty and LipoSaver, was compared.

Methods: Thirty-five patients were enrolled in the study. Patients who underwent VASER2.2 technology were assigned to group 1 (n = 12), patients who underwent LipoSaver2000 technology were assigned to group 2 (n = 12), and patients who underwent SAL were assigned to group 3 (n = 11). For each patient, demographic data, tumescent solution and aspirate volumes, and hemoglobin and hematocrit values in the aspirate were compared.

Results: There was no difference in tumescent volume between the groups, but the aspirate volume from group 3 was significantly higher than the aspirate volume of group 1 (p = 0.001). No difference was detected in terms of Hgb and Hct values in each liter of aspirate, both in terms of the applied liposuction method and TXA application. Additionally, no correlation was observed between gender, age, total inflated volume, total aspirate volume and device use time and Hgb and Htc values in the aspirate.

Conclusion: No significant differences were determined between lipoaspirate, VASER, LipoSaver and SAL in terms of blood loss, and TXA application did not significantly change the Hgb and Htc values in lipoaspirate.

Level of evidence iv: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

查看原文本刊更多论文

氨甲环酸控制吸脂术患者手术失血效果的比较分析。

背景：吸脂术是最流行的整形手术之一，失血是其主要并发症之一。氨甲环酸（TXA）是一种抗纤溶药物，已被证明在许多手术中可以减少失血。在这项前瞻性研究中，比较了TXA对患者失血的影响，这些患者接受了三种不同的手术，包括吸吸辅助脂肪成形术、共振声能振动放大（VASER）辅助脂肪成形术和LipoSaver。方法：35例患者入组。接受VASER2.2技术的患者被分配到1组（n = 12），接受LipoSaver2000技术的患者被分配到2组（n = 12），接受SAL技术的患者被分配到3组（n = 11）。对每位患者的人口学数据、肿胀溶液和吸附剂体积以及吸附剂中的血红蛋白和红细胞压积值进行比较。结果：各组肿胀体积差异无统计学意义，但组3的吸出体积显著高于组1 （p = 0.001）。在每升抽脂方式和TXA应用方面，Hgb和Hct值均无差异。此外，性别、年龄、总充气容积、总抽吸容积和设备使用时间与抽吸器中的Hgb和Htc值之间没有相关性。结论：抽脂液、VASER、LipoSaver和SAL在失血量方面无显著差异，应用TXA对抽脂液Hgb和Htc值无显著影响。证据等级iv：本刊要求作者为每篇文章指定一个证据等级。有关这些循证医学评级的完整描述，请参阅目录或在线作者说明www.springer.com/00266。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Aesthetic Plastic Surgery 医学-外科

CiteScore

4.40

自引率

25.00%

发文量

479

审稿时长

3 months

期刊介绍： Aesthetic Plastic Surgery is a publication of the International Society of Aesthetic Plastic Surgery and the official journal of the European Association of Societies of Aesthetic Plastic Surgery (EASAPS), Società Italiana di Chirurgia Plastica Ricostruttiva ed Estetica (SICPRE), Vereinigung der Deutschen Aesthetisch Plastischen Chirurgen (VDAPC), the Romanian Aesthetic Surgery Society (RASS), Asociación Española de Cirugía Estética Plástica (AECEP), La Sociedad Argentina de Cirugía Plástica, Estética y Reparadora (SACPER), the Rhinoplasty Society of Europe (RSE), the Iranian Society of Plastic and Aesthetic Surgeons (ISPAS), the Singapore Association of Plastic Surgeons (SAPS), the Australasian Society of Aesthetic Plastic Surgeons (ASAPS), the Egyptian Society of Plastic and Reconstructive Surgeons (ESPRS), and the Sociedad Chilena de Cirugía Plástica, Reconstructiva y Estética (SCCP). Aesthetic Plastic Surgery provides a forum for original articles advancing the art of aesthetic plastic surgery. Many describe surgical craftsmanship; others deal with complications in surgical procedures and methods by which to treat or avoid them. Coverage includes "second thoughts" on established techniques, which might be abandoned, modified, or improved. Also included are case histories; improvements in surgical instruments, pharmaceuticals, and operating room equipment; and discussions of problems such as the role of psychosocial factors in the doctor-patient and the patient-public interrelationships. Aesthetic Plastic Surgery is covered in Current Contents/Clinical Medicine, SciSearch, Research Alert, Index Medicus-Medline, and Excerpta Medica/Embase.