When is imaging needed to assess the response to treatment in cardiac amyloidosis.

IF 2 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Current Opinion in Cardiology Pub Date : 2025-09-01 Epub Date: 2025-05-21 DOI:10.1097/HCO.0000000000001236
Shantanu P Sengupta, Prayag Kini
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引用次数: 0

Abstract

Purpose of review: Cardiac amyloidosis is characterized by systolic and diastolic abnormalities due to deposition of amyloid fibril within the myocardial extracellular space. Technological advances in multimodality cardiac imaging now helps in accurate diagnosis and prognosis of this disease. With technological advances in imaging, it is now easier to follow up these patients whether they are getting response to therapy.

Recent findings: Left ventricular global longitudinal strain assessment is an important noninvasive tool to track response to treatment in cardiac amyloidosis patient.

Summary: Present era has shown the importance of using multimodality imaging to understand the pathophysiology of this disease which has been supplemented by both imaging and blood biomarkers. These help in prognosticating the disease burden and to assess treatment response. Future research is now focused on the use of artificial intelligence and precision medicine to detect of changes earlier in the course of treatment.

什么时候需要影像学来评估对心脏淀粉样变性治疗的反应。
回顾目的:心脏淀粉样变性的特点是由于淀粉样纤维沉积在心肌细胞外间隙导致收缩和舒张异常。多模态心脏成像技术的进步现在有助于这种疾病的准确诊断和预后。随着影像技术的进步,现在更容易跟踪这些患者是否对治疗有反应。最近研究发现:左心室整体纵向应变评估是跟踪心脏淀粉样变性患者治疗反应的重要无创工具。摘要:当今时代已经显示了使用多模态成像来了解这种疾病的病理生理学的重要性,这已经得到了成像和血液生物标志物的补充。这些有助于预测疾病负担和评估治疗反应。未来的研究现在集中在使用人工智能和精准医学来检测治疗过程中早期的变化。
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来源期刊
Current Opinion in Cardiology
Current Opinion in Cardiology 医学-心血管系统
CiteScore
4.20
自引率
4.30%
发文量
78
审稿时长
6-12 weeks
期刊介绍: ​​​​​​Current Opinion in Cardiology is a bimonthly publication offering a unique and wide ranging perspective on the key developments in the field. Each issue features hand-picked review articles from our team of expert editors. With fourteen disciplines published across the year – including arrhythmias, molecular genetics, HDL cholesterol and clinical trials – every issue also contains annotated reference detailing the merits of the most important papers.
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