One-year recurrence rate of new-onset atrial fibrillation after acute myocardial infarction

IF 1.6 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Revista Portuguesa De Cardiologia Pub Date : 2025-07-01 DOI:10.1016/j.repc.2024.12.008

Alicia Prieto-Lobato , Víctor Hidalgo Olivares , Manuel Gerónimo Pardo , Marta Cubells Pastor , Francisco Manuel Salmerón Martínez , Miguel José Corbí-Pascual

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Abstract

Introduction and objectives

Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide, with a prevalence of up to 21% in the early phase of acute myocardial infarction (AMI). Data on new-onset AF in this context are limited, and long-term prognosis remains unclear.

Methods

We conducted a retrospective observational cohort study from December 2011 to May 2021, including patients who experienced a first episode of paroxysmal AF during hospitalization for AMI. The primary outcome was the recurrence of AF within the first year post-discharge. Secondary outcomes included all-cause mortality, cardiovascular mortality, and a composite of major adverse cardiovascular events.

Results

A total of 209 patients were included. There was AF recurrence in 19 patients, 9.1% (95% CI 5.2–13.0%) with a median time to recurrence of 84 days (interquartile range 27.5–157.5). While mortality in the AF recurrence group was numerically higher than in the non-AF recurrence group, this difference did not achieve statistical significance (15.8% vs. 7.4%, p=0.19). Patients with AF recurrence had significantly worse prognosis (47.4% vs. 23.7%, p=0.04), primarily due to increased heart failure (HF) hospitalizations.

Conclusions

In patients with a first episode of paroxysmal AF during AMI, one-year recurrence is relatively low (9.1%); however, AF recurrence is associated with significantly worse prognosis, driven largely by HF hospitalizations.

Abstract Image

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急性心肌梗死后新发房颤的1年复发率。

简介和目的：心房颤动（AF）是世界范围内最常见的心律失常，在急性心肌梗死（AMI）早期的患病率高达21%。在这种情况下，新发房颤的数据有限，长期预后仍不清楚。方法：我们从2011年12月至2021年5月进行了一项回顾性观察队列研究，包括因AMI住院期间首次发作阵发性房颤的患者。主要终点是房颤在出院后一年内的复发率。次要结局包括全因死亡率、心血管死亡率和主要心血管不良事件的组合。结果：共纳入209例患者。19例患者房颤复发，9.1% (95% CI 5.2-13.0%)，中位复发时间为84天[四分位数间距27.5-157.5]。虽然房颤复发组的死亡率在数字上高于非房颤复发组，但这种差异没有统计学意义（15.8% vs. 7.4%, p=0.19）。房颤复发患者的预后明显较差（47.4%对23.7%,p=0.04），主要是由于心力衰竭（HF）住院次数增加。结论：AMI期间首发发作阵发性房颤的患者，1年复发率相对较低（9.1%）；然而;房颤复发与明显较差的预后相关，主要由心衰住院所致。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revista Portuguesa De Cardiologia CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

2.70

自引率

22.20%

发文量

205

审稿时长

54 days

期刊介绍： The Portuguese Journal of Cardiology, the official journal of the Portuguese Society of Cardiology, was founded in 1982 with the aim of keeping Portuguese cardiologists informed through the publication of scientific articles on areas such as arrhythmology and electrophysiology, cardiovascular surgery, intensive care, coronary artery disease, cardiovascular imaging, hypertension, heart failure and cardiovascular prevention. The Journal is a monthly publication with high standards of quality in terms of scientific content and production. Since 1999 it has been published in English as well as Portuguese, which has widened its readership abroad. It is distributed to all members of the Portuguese Societies of Cardiology, Internal Medicine, Pneumology and Cardiothoracic Surgery, as well as to leading non-Portuguese cardiologists and to virtually all cardiology societies worldwide. It has been referred in Medline since 1987.