EBV: The Viral Genome.

3区医学 Q2 Medicine

Current topics in microbiology and immunology Pub Date : 2025-05-22 DOI:10.1007/82_2025_298

Paul J Farrell

引用次数: 0

Abstract

The Epstein-Barr virus (EBV) genetic map underpins all our understanding of the virus biology and its role in disease. EBV was the first large DNA virus to be fully sequenced and this has been followed by many years of detailed mapping of viral genes and other genetic elements. The genetic map of EBV is based on the reference NC_007605 virus genome but now more than 1,000 EBV genomes have been sequenced. Some sequence variations that may be functionally significant either for the biological properties of EBV or its detection by diagnostic procedures are summarised here but are also considered in detail in other chapters in this book.

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EBV：病毒基因组

eb病毒（EBV）基因图谱巩固了我们对病毒生物学及其在疾病中的作用的所有理解。EBV是第一个被完全测序的大型DNA病毒，随后多年来一直在详细绘制病毒基因和其他遗传元素。EBV的遗传图谱是基于参考的NC_007605病毒基因组，但现在已经对1000多个EBV基因组进行了测序。一些序列变异可能对EBV的生物学特性或诊断程序的检测具有重要的功能，在这里进行了总结，但也在本书的其他章节中进行了详细讨论。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current topics in microbiology and immunology 医学-免疫学

CiteScore

5.60

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The review series Current Topics in Microbiology and Immunology provides a synthesis of the latest research findings in the areas of molecular immunology, bacteriology and virology. Each timely volume contains a wealth of information on the featured subject. This review series is designed to provide access to up-to-date, often previously unpublished information.