Application of high intensity focused ultrasound in the treatment of uterine fibroids in overweight/obese women.

IF 2.4 3区 医学 Q2 OBSTETRICS & GYNECOLOGY
Lijing Wu, Liying Zhong, Qingyan Zheng, Lingna Huang, Fengning Lin, Zhiwei Chen, Chengying Lian
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Abstract

Objective: To investigate the clinical efficacy and safety of High-Intensity Focused Ultrasound (HIFU) in the treatment of uterine fibroids in overweight/obese women.

Methods: A retrospective analysis was conducted on the clinical data of 155 overweight/obese women with uterine fibroids treated at our hospital between January 2022 and January 2024. Among them, 75 patients underwent HIFU treatment (observation group), while 80 patients received conventional laparoscopic myomectomy (control group). Perioperative indicators, symptom improvement (assessed by the Symptom Severity Score, SSS), health-related quality of life (HRQL score), complications, and recurrence rates at 1-year post-treatment were compared between the two groups.

Results: All procedures were successfully completed in both groups. No significant differences were observed in baseline characteristics such as age, BMI, number of fibroids, maximum fibroid diameter, and hemoglobin levels between the two groups (P > 0.05). At 6 months and 1 year post-treatment, the observation group showed significantly better SSS scores (12.61 ± 1.22 vs. 15.89 ± 1.21; 10.40 ± 1.27 vs. 12.03 ± 1.33) and HRQL scores (89.35 ± 1.90 vs. 84.69 ± 1.24; 94.19 ± 1.16 vs. 91.69 ± 1.32) compared to the control group (P < 0.05). The total complication rate in the observation group was significantly lower than that in the control group (9.33% vs. 21.3%, χ² = 4.34, P = 0.04). No recurrence or fibroid enlargement was observed in the observation group at 1-year follow-up.

Conclusion: HIFU is an effective and safe treatment for uterine fibroids in overweight/obese women, offering advantages such as minimal invasiveness, fewer complications, and faster recovery. It represents a superior minimally invasive option for this patient population.

高强度聚焦超声在超重/肥胖妇女子宫肌瘤治疗中的应用。
目的:探讨高强度聚焦超声(HIFU)治疗超重/肥胖女性子宫肌瘤的临床疗效和安全性。方法:回顾性分析2022年1月至2024年1月在我院治疗的155例超重/肥胖子宫肌瘤患者的临床资料。其中75例患者行HIFU治疗(观察组),80例患者行常规腹腔镜子宫肌瘤切除术(对照组)。比较两组围手术期指标、症状改善(用症状严重程度评分(SSS)评估)、健康相关生活质量(HRQL评分)、并发症和治疗后1年复发率。结果:两组患者均顺利完成手术。两组患者的年龄、BMI、肌瘤数、肌瘤最大直径、血红蛋白水平等基线指标差异无统计学意义(P < 0.05)。治疗后6个月和1年,观察组患者SSS评分显著高于对照组(12.61±1.22∶15.89±1.21;10.40±1.27和12.03±1.33)和HRQL得分(89.35±1.90和84.69±1.24;结论:HIFU治疗超重/肥胖女性子宫肌瘤具有微创、并发症少、恢复快等优点,是一种安全有效的治疗方法。它代表了一个优越的微创选择的患者群体。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
BMC Women's Health
BMC Women's Health OBSTETRICS & GYNECOLOGY-
CiteScore
3.40
自引率
4.00%
发文量
444
审稿时长
>12 weeks
期刊介绍: BMC Women''s Health is an open access, peer-reviewed journal that considers articles on all aspects of the health and wellbeing of adolescent girls and women, with a particular focus on the physical, mental, and emotional health of women in developed and developing nations. The journal welcomes submissions on women''s public health issues, health behaviours, breast cancer, gynecological diseases, mental health and health promotion.
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