Effects of dietary medium-chain fatty acid supplementation levels on growth performance, blood parameters, fecal sore and metabolites in nursery pigs.

IF 2.4 2区农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE

Animal Bioscience Pub Date : 2025-05-19 DOI:10.5713/ab.25.0099

Chan Ho Kwon, Jannell A Torres, Madison J Mejia, Eva S Safaie, Joseph G Usack, Young Dal Jang

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Abstract

Objective: This study evaluated the effects of increasing medium-chain fatty acid (MCFA) supplementation levels on growth performance, blood parameters, fecal score, and metabolites in nursery pigs.

Methods: A total of 100 newly weaned pigs (initial body weight: 6.68 ± 0.97 kg) were allotted to 5 treatments in 5 replicates, with 4 pigs per pen for a 28-d feeding trial. Treatments were MCFA supplementation levels at 0.0, 0.4, 0.8, 1.2, and 1.6%. The 2% soybean oil in the basal diet was replaced with MCFA (a 50:50 blend of free caproic and caprylic acids) on a weight-to-weight basis. Growth performance, fecal score, blood, and fecal characteristics were measured.

Results: Increasing MCFA supplementation levels tended to linearly increase the final body weight (p=0.06) and average daily gain in the overall period (p=0.06), with no difference in overall average daily feed intake. The gain-to-feed ratio increased linearly in d 7-14 (p=0.06, tendency) and 14-21 postweaning (p<0.05). Fecal score linearly decreased in d 0-7, 7-14, and 14-21 (p<0.05) postweaning, resulting in a linear reduction in the overall period (p<0.05). Plasma malondialdehyde levels at d 28 postweaning showed a quadratic decrease with increasing MCFA levels with the lowest value at 0.8% (p<0.05). Plasma free fatty acid levels at d 14 postweaning linearly decreased with increasing MCFA supplementation levels (p<0.05). Fecal total short-chain fatty acid (SCFA) concentrations tended to be lower (p=0.09, tendency) in the MCFA treatments (0.4-1.6%) than the control treatment (0.0%). There were no differences in plasma superoxide dismutase activity and fecal ammonia concentrations among dietary treatments.

Conclusion: Increasing MCFA supplementation levels up to 1.6% could improve growth rate, feed efficiency, and fecal consistency without affecting feed intake and have the potential to reduce oxidative stress and free fatty acid levels in weaning pigs, while fecal SCFA concentrations could be slightly reduced by MCFA supplementation.

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饲粮中链脂肪酸添加水平对苗猪生长性能、血液参数、粪便溃疡及代谢物的影响

目的：本研究旨在评价中链脂肪酸（MCFA）添加水平对苗猪生长性能、血液指标、粪便评分和代谢物的影响。方法：选用100头初断奶仔猪（初体重：6.68±0.97 kg），随机分为5个处理，分5个重复，每个栏4头猪，饲喂28 d。各组MCFA添加水平分别为0.0、0.4、0.8、1.2和1.6%。将基础饲粮中2%的大豆油按体重比例替换为MCFA（游离己酸和辛酸50:50的混合物）。测量生长性能、粪便评分、血液和粪便特征。结果：增加MCFA添加水平有增加末重（p=0.06）和全期平均日增重（p=0.06）的趋势，对全期平均日采食量无显著影响。断奶后7-14 d和14-21 d增重比呈线性增加（p=0.06，趋势）。结论：添加1.6%的MCFA可在不影响采食量的情况下提高断奶仔猪的生长速度、饲料效率和粪便稠度，并有可能降低断奶仔猪的氧化应激和游离脂肪酸水平，而添加MCFA可轻微降低粪便SCFA浓度。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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