A Comprehensive Review of Two-Dimensional Speckle-Tracking Echocardiography in Assessing Right and Left Ventricular Function in Diabetic Patients

IF 2.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Clinical Cardiology Pub Date : 2025-05-22 DOI:10.1002/clc.70153

Azin Alizadehasl, Mahshid Mokhayeri, Zeynab Sohani, Mohammad Yasin Zamanian, Parai Shahbazi, Shiva Borzouei

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Abstract

Background

Two-dimensional speckle-tracking echocardiography (2D-STE) has emerged as a valuable tool for assessing cardiac function in patients with type 1 (T1DM) and type 2 diabetes mellitus (T2DM).

Hypothesis

This review synthesizes recent studies utilizing 2D-STE in diabetic patients, highlighting its clinical applications and findings.

Methods

In this review, relevant studies were identified through comprehensive searches of major scientific databases, including PubMed, Scopus, Google Scholar, ScienceDirect, and other reputable sources.

Results

The results of this study indicate that 2D-STE is capable of detecting subclinical cardiac dysfunction in patients with both T1DM and T2DM, even in instances where conventional echocardiographic parameters appear to be within normal limits. Assessment of right ventricular (RV) function through 2D-STE has demonstrated impaired right ventricular free wall longitudinal strain (RVFWLS) and global longitudinal strain (RVGLS) in individuals with T2DM, which correlates with suboptimal glycemic control. Furthermore, evaluation of left ventricular (LV) function has revealed decreased global longitudinal strain (GLS) and impaired LV twist mechanics in T2DM patients, particularly under conditions of physiological stress.

In T1DM patients, 2D-STE has identified early changes in myocardial deformation, with studies reporting reduced LV and RV strain values compared to healthy controls. The technique has also been effective in assessing the impact of disease duration and glycemic control on cardiac function in both T1DM and T2DM.

Conclusions

These findings underscore the potential of 2D-STE as a sensitive and comprehensive tool for early detection of cardiac dysfunction in both T1DM and T2DM, potentially guiding management strategies and improving outcomes in these high-risk populations.

Abstract Image

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二维斑点跟踪超声心动图评价糖尿病患者左右心室功能的综述

二维斑点跟踪超声心动图（2D-STE）已成为评估1型（T1DM）和2型糖尿病（T2DM）患者心功能的一种有价值的工具。本文综述了近期在糖尿病患者中应用2D-STE的研究，重点介绍了其临床应用和发现。方法通过综合检索PubMed、Scopus、谷歌Scholar、ScienceDirect等知名科学数据库，筛选相关研究。本研究结果表明，2D-STE能够检测T2DM和T1DM患者的亚临床心功能障碍，即使在常规超声心动图参数在正常范围内的情况下也是如此。通过2D-STE评估右心室（RV）功能表明，T2DM患者右心室游离壁纵向应变（RVFWLS）和整体纵向应变（RVGLS）受损，这与血糖控制不佳有关。此外，对左心室（LV）功能的评估显示，T2DM患者整体纵向应变（GLS）下降，左心室扭转力学受损，尤其是在生理应激条件下。在T1DM患者中，2D-STE发现了心肌变形的早期变化，研究报告与健康对照组相比，左室和右室应变值降低。该技术在评估T1DM和T2DM患者病程和血糖控制对心功能的影响方面也很有效。这些发现强调了2D-STE作为早期检测T1DM和T2DM心功能障碍的敏感和全面工具的潜力，可能指导这些高危人群的管理策略和改善预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Cardiology 医学-心血管系统

CiteScore

5.10

自引率

3.70%

发文量

189

审稿时长

4-8 weeks

期刊介绍： Clinical Cardiology provides a fully Gold Open Access forum for the publication of original clinical research, as well as brief reviews of diagnostic and therapeutic issues in cardiovascular medicine and cardiovascular surgery. The journal includes Clinical Investigations, Reviews, free standing editorials and commentaries, and bonus online-only content. The journal also publishes supplements, Expert Panel Discussions, sponsored clinical Reviews, Trial Designs, and Quality and Outcomes.