Multi-Layer Tissue-Mimicking Breast Phantoms for Microwave-Based Imaging Systems

IF 3.2 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC
Simona Di Meo;Alessia Cannatà;Carolina Blanco-Angulo;Giulia Matrone;Andrea Martínez-Lozano;Julia Arias-Rodríguez;José M. Sabater-Navarro;Roberto Gutiérrez-Mazón;Héctor García-Martínez;Ernesto Ávila-Navarro;Marco Pasian
{"title":"Multi-Layer Tissue-Mimicking Breast Phantoms for Microwave-Based Imaging Systems","authors":"Simona Di Meo;Alessia Cannatà;Carolina Blanco-Angulo;Giulia Matrone;Andrea Martínez-Lozano;Julia Arias-Rodríguez;José M. Sabater-Navarro;Roberto Gutiérrez-Mazón;Héctor García-Martínez;Ernesto Ávila-Navarro;Marco Pasian","doi":"10.1109/JERM.2024.3379750","DOIUrl":null,"url":null,"abstract":"This study contributesto the ongoing progress in microwave-based breast tumor detection systems, recognizing their potential advantages over traditional detection techniques. This research centers on the development of more realistic breast phantoms with precise dielectric properties, which are essential for evaluating these innovative systems. A key highlight is the implementation of a thorough two-step procedure for crafting multi-layer breast phantoms that faithfully replicate actual breast tissues. To validate the accuracy of these phantoms, dielectric measurements were conducted, spanning frequencies up to 40 GHz. This procedure extends to the development of complex two and three-layer breast phantoms. Importantly, our research shows that the multi-step procedure for preparing heterogeneous phantoms maintains the dielectric properties of the mixtures, ensuring their reliability. A microwave-based tumor detection system, equipped with 16 broadband antennas and advanced algorithms, underwent rigorous testing using these phantoms. The results are highly promising, showcasing the system's remarkable ability to detect tumors while also successfully identifying and addressing artifacts in the generated images. This underscores the significance of this research as a substantial advancement in microwave-based breast tumor detection systems, mainly credited to the development of more realistic two and three-layer breast phantoms. The clinical implications are substantial, particularly for cases involving dense breast tissue, a common characteristic among younger patients. These innovations have the potential to transform breast cancer screening by providing enhanced accuracy and early detection capabilities.","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":"9 2","pages":"157-165"},"PeriodicalIF":3.2000,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","FirstCategoryId":"1085","ListUrlMain":"https://ieeexplore.ieee.org/document/10487989/","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, ELECTRICAL & ELECTRONIC","Score":null,"Total":0}
引用次数: 0

Abstract

This study contributesto the ongoing progress in microwave-based breast tumor detection systems, recognizing their potential advantages over traditional detection techniques. This research centers on the development of more realistic breast phantoms with precise dielectric properties, which are essential for evaluating these innovative systems. A key highlight is the implementation of a thorough two-step procedure for crafting multi-layer breast phantoms that faithfully replicate actual breast tissues. To validate the accuracy of these phantoms, dielectric measurements were conducted, spanning frequencies up to 40 GHz. This procedure extends to the development of complex two and three-layer breast phantoms. Importantly, our research shows that the multi-step procedure for preparing heterogeneous phantoms maintains the dielectric properties of the mixtures, ensuring their reliability. A microwave-based tumor detection system, equipped with 16 broadband antennas and advanced algorithms, underwent rigorous testing using these phantoms. The results are highly promising, showcasing the system's remarkable ability to detect tumors while also successfully identifying and addressing artifacts in the generated images. This underscores the significance of this research as a substantial advancement in microwave-based breast tumor detection systems, mainly credited to the development of more realistic two and three-layer breast phantoms. The clinical implications are substantial, particularly for cases involving dense breast tissue, a common characteristic among younger patients. These innovations have the potential to transform breast cancer screening by providing enhanced accuracy and early detection capabilities.
用于微波成像系统的多层组织模拟乳房幻象
这项研究促进了基于微波的乳腺肿瘤检测系统的持续发展,认识到它们比传统检测技术具有潜在的优势。本研究的重点是开发具有精确介电特性的更逼真的乳房模型,这对于评估这些创新系统至关重要。一个关键的亮点是执行一个彻底的两步程序,制作多层乳房模型,忠实地复制真实的乳房组织。为了验证这些幻影的准确性,进行了介电测量,频率高达40 GHz。这个过程延伸到复杂的两层和三层乳房幻影的发展。重要的是,我们的研究表明,制备异质幻影的多步骤过程保持了混合物的介电性能,确保了它们的可靠性。一个基于微波的肿瘤检测系统,配备了16个宽带天线和先进的算法,使用这些幽灵进行了严格的测试。结果非常有希望,展示了该系统在检测肿瘤的同时成功识别和处理生成图像中的伪影的卓越能力。这强调了这项研究的重要性,因为微波乳房肿瘤检测系统取得了实质性进展,主要归功于更真实的两层和三层乳房幻象的发展。临床意义是重大的,特别是涉及致密乳腺组织的病例,这是年轻患者的共同特征。这些创新有可能通过提供更高的准确性和早期检测能力来改变乳腺癌筛查。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
5.80
自引率
9.40%
发文量
58
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信