Nanomaterials for delivery of medicinal plant extracts and phytochemicals: Potential applications and future perspectives

Plant Nano Biology Pub Date : 2025-05-01 DOI:10.1016/j.plana.2025.100161

Subhojit Ghosh , Raghu Solanki , Dhiraj Bhatia, Subramanian Sankaranarayanan

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Abstract

Nature has been an immense reservoir of therapeutic agents derived from medicinal plants. Bioactive compounds isolated from these plants have demonstrated significant pharmacological potential across a range of medical applications, including cancer therapy, cardiovascular and neuroprotective effects, antimicrobial activity, wound healing, and anti-inflammatory effects. Despite their remarkable therapeutic potential, the clinical translation of these phytochemicals is restricted by challenges such as poor solubility, limited stability, and non-specific distribution. Recent advancements in nanotechnology have revolutionized their delivery by addressing these limitations. Nano-based approaches for delivery of medicinal plant extracts and phytochemicals have emerged as promising strategies in the development of advanced drug delivery systems. This review presents a comprehensive overview of recent progress in nanomaterial-mediated delivery of medicinal plant extracts and phytochemicals, highlighting their transformative potential in overcoming traditional limitations and addressing complex therapeutic needs in modern healthcare.

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药用植物提取物和植物化学物质的纳米递送材料：潜在应用和未来展望

自然界一直是药用植物衍生的治疗剂的巨大储存库。从这些植物中分离出的生物活性化合物在一系列医学应用中显示出显著的药理潜力，包括癌症治疗、心血管和神经保护作用、抗菌活性、伤口愈合和抗炎作用。尽管具有显著的治疗潜力，但这些植物化学物质的临床转化受到诸如溶解性差、稳定性有限和非特异性分布等挑战的限制。纳米技术的最新进展通过解决这些限制已经彻底改变了它们的交付方式。药用植物提取物和植物化学物质的纳米递送方法已经成为开发先进药物递送系统的有前途的策略。本文综述了纳米材料介导的药用植物提取物和植物化学物质递送的最新进展，强调了它们在克服传统限制和解决现代医疗保健中复杂治疗需求方面的变革潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Plant Nano Biology

CiteScore

2.80

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0.00%

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