The efficacy of mindfulness-based cognitive therapy in regulating cognition and emotion of patients with depression: A systematic review of randomized controlled trials

Q3 Psychology

Journal of Affective Disorders Reports Pub Date : 2025-05-16 DOI:10.1016/j.jadr.2025.100929

Nikapitiye Nandarathana, Jay Kumar Ranjan, Madhubanti Sinha

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Abstract

Background

A number of reviews report the efficacy of Mindfulness-Based Cognitive Therapy (MBCT) in the treatment of depressive disorders, however, there is a dearth of qualitative reviews examining the efficacy of MBCT in regulating cognitions and emotions.

Objective

To systematically review the efficacy of MBCT in alleviating depressive symptoms, preventing relapse in patients with depression (PWD), and identify the different cognitive and affective factors that influence its effectiveness.

Methods

A comprehensive search was conducted in six electronic databases (PubMed, EBSCOhost, Web of Science, JSTOR, Scopus, and Science Direct) up to May 13, 2024 for randomized controlled trials (RCTs) assessing MBCT in adults with depressive disorders. We appraised the methodological quality of the included studies using Cochrane Risk-of-Bias 2.0.

Results

The present systematic review followed the PRISMA guideline, and out of 1151 screened studies, 117 were eligible for full-text review. 17 studies were finally included in this review. All included studies utilized RCTs, comparing MBCT vs treatment as usual (TAU) and one study compares MBCT with cognitive behavioral therapy (CBT) and TAU. The results support that MBCT effectively manages the symptoms of depressive disorders and regulates cognition and emotions.

Conclusion

MBCT, when implemented with pharmacological treatment, demonstrates significant efficacy in alleviating depressive symptoms, reducing thought rumination, regulating emotions, and enhancing mindfulness. Further, MBCT reduces relapse rates in patients with depression.

PROSPERO registration

CRD42024548497

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正念认知疗法调节抑郁症患者认知和情绪的疗效：随机对照试验的系统综述

背景：许多综述报道了正念认知疗法（MBCT）治疗抑郁症的疗效，然而，关于MBCT在调节认知和情绪方面的疗效的定性综述却很少。目的系统回顾MBCT在缓解抑郁症（PWD）患者抑郁症状、预防复发方面的疗效，并探讨影响其疗效的不同认知和情感因素。方法综合检索截至2024年5月13日的6个电子数据库（PubMed、EBSCOhost、Web of Science、JSTOR、Scopus和Science Direct）中评估成人抑郁症MBCT的随机对照试验（RCTs）。我们使用Cochrane风险偏倚2.0评价纳入研究的方法学质量。本系统综述遵循PRISMA指南，在1151项筛选研究中，有117项符合全文综述的条件。17项研究最终纳入本综述。所有纳入的研究均采用随机对照试验，比较MBCT与常规治疗（TAU），一项研究将MBCT与认知行为治疗（CBT）和TAU进行比较。结果支持MBCT有效管理抑郁症的症状，调节认知和情绪。结论mbct配合药物治疗在缓解抑郁症状、减少思想反刍、调节情绪、增强正念等方面具有显著疗效。此外，MBCT还能降低抑郁症患者的复发率。普洛斯彼罗registrationCRD42024548497

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