A Reset for Bioethics: A Statement from the Global Observatory for Genome Editing.

IF 3.7 4区 生物学 Q2 GENETICS & HEREDITY
Sheila Jasanoff, J Benjamin Hurlbut, Krishanu Saha, Jacob D Moses, Daniel Affsprung, Henry Austin, Françoise Baylis, John H Evans, Timothy Hunt, Douglas A Kysar, Laurence Lwoff, Peter Mills, Jahnavi Phalkey, Matthew H Porteus, O Carter Snead, Kaushik Sunder Rajan, Carrie D Wolinetz
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引用次数: 0

Abstract

How should we govern our increasing power to intervene in the processes of life? Genome editing, especially of the human germline, has brought this question to the forefront of global debate. We must seek to rectify shortcomings of earlier deliberative approaches by setting aside a science-and-technology first approach; expanding the range of questions for deliberation; revisiting the distribution of innovation's benefits and risks; and reimagining the limits of research. This Perspective from the Organizing Committee of the 2025 Global Observatory for Genome Editing International Summit calls for a new social compact, recognizing and rendering accountable the constitutive role of science and technology in shaping the meaning of human life in the 21st century.

生物伦理的重置:基因组编辑全球观察站的声明。
我们应该如何管理我们日益增强的干预生命过程的能力呢?基因组编辑,特别是人类生殖系的基因组编辑,使这个问题成为全球辩论的前沿。我们必须放弃科学和技术优先的办法,设法纠正以前审议办法的缺点;扩大审议问题范围;重新审视创新的收益与风险分配;重新想象研究的极限。2025年基因组编辑全球观察站国际峰会组委会的这一展望呼吁制定一项新的社会契约,承认并问责科学和技术在塑造21世纪人类生活意义方面的构成性作用。
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来源期刊
CRISPR Journal
CRISPR Journal Biochemistry, Genetics and Molecular Biology-Biotechnology
CiteScore
6.30
自引率
2.70%
发文量
76
期刊介绍: In recognition of this extraordinary scientific and technological era, Mary Ann Liebert, Inc., publishers recently announced the creation of The CRISPR Journal -- an international, multidisciplinary peer-reviewed journal publishing outstanding research on the myriad applications and underlying technology of CRISPR. Debuting in 2018, The CRISPR Journal will be published online and in print with flexible open access options, providing a high-profile venue for groundbreaking research, as well as lively and provocative commentary, analysis, and debate. The CRISPR Journal adds an exciting and dynamic component to the Mary Ann Liebert, Inc. portfolio, which includes GEN (Genetic Engineering & Biotechnology News) and more than 80 leading peer-reviewed journals.
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