Liver frailty and impact of liver transplants on transplanted patients' health.

IF 1.5 4区医学 Q3 NURSING

Revista Latino-Americana De Enfermagem Pub Date : 2025-05-19 eCollection Date: 2025-01-01 DOI:10.1590/1518-8345.7330.4563

Victor Fernandez-Alonso, Ana Maria Hernandez-Matias, Manuela Perez-Gomez, Leyre Rodriguez-Leal, Maria Nieves Moro-Tejedor

{"title":"Liver frailty and impact of liver transplants on transplanted patients' health.","authors":"Victor Fernandez-Alonso, Ana Maria Hernandez-Matias, Manuela Perez-Gomez, Leyre Rodriguez-Leal, Maria Nieves Moro-Tejedor","doi":"10.1590/1518-8345.7330.4563","DOIUrl":null,"url":null,"abstract":"to analyse the Liver Frailty Index in a cohort of patients from their inclusion in the waiting list to one year after the liver transplant.a cohort study with patients included in a liver transplant waiting list from January 2020 to December 2021. The variables were analysed and the hypothesis were contrasted by means of the Mann-Whitney U and Spearman's correlation test, a paired measures test and multivariate analysis.the sample consisted in n=51 patients with a mean age of 57.20 years old (SD=9.70), with 74.50% of men. The mean pre-transplant Liver Frailty index was 3.71 (SD=0.74), reaching higher values in patients with advanced liver disease (p=0.004), alcohol-related etiology (p=0.039) and unemployed (p=0.014). Liver frailty improved after the transplant (p<0.001), keeping a directly proportional correlation with age (p=0.014).advanced liver disease, etiology related to alcohol and time in the waiting list exert impacts on liver frailty during the liver transplant process. Older liver transplanted patients are more frail.","PeriodicalId":48692,"journal":{"name":"Revista Latino-Americana De Enfermagem","volume":"33 ","pages":"e4563"},"PeriodicalIF":1.5000,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12088654/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Latino-Americana De Enfermagem","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1590/1518-8345.7330.4563","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"NURSING","Score":null,"Total":0}

引用次数: 0

Abstract

to analyse the Liver Frailty Index in a cohort of patients from their inclusion in the waiting list to one year after the liver transplant.

a cohort study with patients included in a liver transplant waiting list from January 2020 to December 2021. The variables were analysed and the hypothesis were contrasted by means of the Mann-Whitney U and Spearman's correlation test, a paired measures test and multivariate analysis.

the sample consisted in n=51 patients with a mean age of 57.20 years old (SD=9.70), with 74.50% of men. The mean pre-transplant Liver Frailty index was 3.71 (SD=0.74), reaching higher values in patients with advanced liver disease (p=0.004), alcohol-related etiology (p=0.039) and unemployed (p=0.014). Liver frailty improved after the transplant (p<0.001), keeping a directly proportional correlation with age (p=0.014).

advanced liver disease, etiology related to alcohol and time in the waiting list exert impacts on liver frailty during the liver transplant process. Older liver transplanted patients are more frail.

查看原文本刊更多论文

肝移植后肝脏衰弱及对移植患者健康的影响。

分析一组患者从他们被列入等候名单到肝移植后一年的肝脏衰弱指数。这是一项队列研究，研究对象是2020年1月至2021年12月肝移植等待名单上的患者。采用Mann-Whitney U和Spearman相关检验、配对测量检验和多变量分析对变量进行分析，并对假设进行对比。样本包括51例患者，平均年龄57.20岁（SD=9.70），男性占74.50%。移植前肝脏脆弱指数平均为3.71 (SD=0.74)，晚期肝病（p=0.004）、酒精相关病因（p=0.039）和失业（p=0.014）患者的肝脏脆弱指数更高。肝移植后肝脏衰弱得到改善（晚期肝病、酒精相关病因及等待时间对肝移植过程中肝脏衰弱有影响）。年龄较大的肝移植患者更虚弱。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Revista Latino-Americana De Enfermagem NURSING-

自引率

11.10%

发文量

142

期刊介绍： A Revista Latino-Americana de Enfermagem constitui-se no órgão oficial de divulgação científica da Escola de Enfermagem de Ribeirão Preto da Universidade de São Paulo e do Centro Colaborador da OMS para o Desenvolvimento da Pesquisa em Enfermagem. Foi criada em abril de 1992 sendo sua primeira edição publicada em janeiro de 1993. No período de 1993 a 1997 tinha periodicidade semestral, de 1997 a 2000 trimestral e, a partir de janeiro de 2001, tem periodicidade bimestral. Caracteriza-se como periódico de circulação internacional, abrangendo predominantemente os países da América Latina e Caribe, embora seja também divulgado para assinantes dos Estados Unidos, Portugal e Espanha.