Dynamic Airway CT for Morphometric Analysis of Pediatric Tracheomalacia Throughout Respiration.

IF 2.6 3区 医学 Q1 OTORHINOLARYNGOLOGY
Hannah F Case, Michael Bindschadler, Michael Barbour, Tanya Meyer, John P Dahl, Seth D Friedman, Alberto Aliseda, Randall A Bly
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引用次数: 0

Abstract

Dynamic airway computed topography (4D-CT) can be used to evaluate the trachea in pediatric patients with tracheomalacia. The 4D-CT enables objective and quantitative evaluation throughout all phases of respiration; however, current systems focus on qualitative review of generated 4D images. Few analytic workflows are available to assist in the extraction of the quantitative geomorphic data generated. In this study, we share a protocol developed within the 3D Slicer framework that performs semi-automatic tracheal segmentation and subsequent geomorphic analysis. This methodology is applied to 4 sample cases with varying degrees of tracheal collapse throughout all phases of respiration to demonstrate output of cross-sectional area, aspect ratio (defined as the ratio between minor-to-major luminal axis lengths), and tracheal volume (bound by the subglottis and carina) metrics.

儿童呼吸过程中气管软化症的动态气道CT形态学分析。
动态气道计算机地形图(4D-CT)可用于评估儿童气管软化症患者的气管。4D-CT能够在呼吸的所有阶段进行客观和定量的评估;然而,目前的系统侧重于对生成的4D图像进行定性审查。很少有分析工作流程可用于协助提取所生成的定量地貌数据。在这项研究中,我们共享了在3D切片器框架内开发的协议,该协议执行半自动气管分割和随后的地貌分析。该方法应用于4例在呼吸的所有阶段有不同程度的气管塌陷的样本病例,以展示横截面积、纵横比(定义为小管轴长度与大管轴长度之间的比率)和气管体积(由声门下和隆突结合)指标的输出。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Otolaryngology- Head and Neck Surgery
Otolaryngology- Head and Neck Surgery 医学-耳鼻喉科学
CiteScore
6.70
自引率
2.90%
发文量
250
审稿时长
2-4 weeks
期刊介绍: Otolaryngology–Head and Neck Surgery (OTO-HNS) is the official peer-reviewed publication of the American Academy of Otolaryngology–Head and Neck Surgery Foundation. The mission of Otolaryngology–Head and Neck Surgery is to publish contemporary, ethical, clinically relevant information in otolaryngology, head and neck surgery (ear, nose, throat, head, and neck disorders) that can be used by otolaryngologists, clinicians, scientists, and specialists to improve patient care and public health.
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