Efficacy and Safety of Lasers in Treating Head and Neck Capillary Malformations: A Systematic Review and Meta-analysis.

IF 2.6 3区医学 Q1 OTORHINOLARYNGOLOGY

Otolaryngology- Head and Neck Surgery Pub Date : 2025-05-21 DOI:10.1002/ohn.1309

Soroush Farsi, Peter Eckard, Walker Bartels, Peyton Pinkus, Gresham T Richter

{"title":"Efficacy and Safety of Lasers in Treating Head and Neck Capillary Malformations: A Systematic Review and Meta-analysis.","authors":"Soroush Farsi, Peter Eckard, Walker Bartels, Peyton Pinkus, Gresham T Richter","doi":"10.1002/ohn.1309","DOIUrl":null,"url":null,"abstract":"Objective: This study aims to comprehensively review and compare the safety and efficacy of commonly used lasers in the management of head and neck capillary malformations (CMs).Data sources: PubMed, Embase, Cochrane, and Web of Science.Review methods: Databases were searched from inception to August 2023. Study protocols adhered to the PRISMA guidelines. Cohort studies reporting CM laser treatment outcomes were included. Study validity was tested using the Newcastle-Ottawa Scale. Meta-analysis was conducted using the inverse variance method and a fixed effects model, with treatment success defined as achieving 25% to 100% clearance of the lesion.Results: A total of 725 studies were screened, and 14 full-text articles met the criteria, comprising 714 patients. Patients underwent a mean of 6.5 laser treatment sessions, consisting of 80% pulsed dye laser (PDL), 12% neodymium-doped yttrium-aluminum-garnet laser (Nd:YAG), and 8% 577 nm yellow laser treatments. Meta-analysis revealed an overall treatment success rate of 97% (95% confidence interval [CI]: 0.96-0.98). Subgroup analysis by laser type resulted a success rate of 96% (95% CI: 0.94-0.973) for PDL, 99% (95% CI: 0.979-1.008) for Nd:YAG laser, and 86% (95% CI: 0.7621-0.964) for 577 nm yellow laser. The complication rate by laser type was 9% (95% CI: 0.031-0.147) for PDL, 4% (95% CI: 0.007-0.080) for Nd:YAG laser, and no reported complication data for 577 nm yellow laser.Conclusion: The vast majority of the available data on laser treatment of head and neck CMs suggest excellent outcomes and low complication rate using PDL treatment. Centers using Nd:YAG laser reported a slightly higher rate of successful treatment with fewer complications than PDL or 577 nm yellow laser treatment.","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":2.6000,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Otolaryngology- Head and Neck Surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/ohn.1309","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: This study aims to comprehensively review and compare the safety and efficacy of commonly used lasers in the management of head and neck capillary malformations (CMs).

Data sources: PubMed, Embase, Cochrane, and Web of Science.

Review methods: Databases were searched from inception to August 2023. Study protocols adhered to the PRISMA guidelines. Cohort studies reporting CM laser treatment outcomes were included. Study validity was tested using the Newcastle-Ottawa Scale. Meta-analysis was conducted using the inverse variance method and a fixed effects model, with treatment success defined as achieving 25% to 100% clearance of the lesion.

Results: A total of 725 studies were screened, and 14 full-text articles met the criteria, comprising 714 patients. Patients underwent a mean of 6.5 laser treatment sessions, consisting of 80% pulsed dye laser (PDL), 12% neodymium-doped yttrium-aluminum-garnet laser (Nd:YAG), and 8% 577 nm yellow laser treatments. Meta-analysis revealed an overall treatment success rate of 97% (95% confidence interval [CI]: 0.96-0.98). Subgroup analysis by laser type resulted a success rate of 96% (95% CI: 0.94-0.973) for PDL, 99% (95% CI: 0.979-1.008) for Nd:YAG laser, and 86% (95% CI: 0.7621-0.964) for 577 nm yellow laser. The complication rate by laser type was 9% (95% CI: 0.031-0.147) for PDL, 4% (95% CI: 0.007-0.080) for Nd:YAG laser, and no reported complication data for 577 nm yellow laser.

Conclusion: The vast majority of the available data on laser treatment of head and neck CMs suggest excellent outcomes and low complication rate using PDL treatment. Centers using Nd:YAG laser reported a slightly higher rate of successful treatment with fewer complications than PDL or 577 nm yellow laser treatment.

查看原文本刊更多论文

激光治疗头颈部毛细血管畸形的有效性和安全性：系统回顾和荟萃分析。

目的：对常用激光治疗头颈部毛细血管畸形（CMs）的安全性和有效性进行综述和比较。数据来源：PubMed， Embase， Cochrane和Web of Science。回顾方法：检索数据库自成立至2023年8月。研究方案遵循PRISMA指南。包括报道CM激光治疗结果的队列研究。研究效度采用纽卡斯尔-渥太华量表进行检验。采用反方差法和固定效应模型进行meta分析，治疗成功定义为病灶清除率达到25%至100%。结果：共有725项研究被筛选，14篇全文文章符合标准，包括714名患者。患者平均接受6.5次激光治疗，包括80%脉冲染料激光（PDL）， 12%掺钕钇铝石榴石激光（Nd:YAG）和8% 577 nm黄色激光治疗。meta分析显示总体治疗成功率为97%（95%可信区间[CI]: 0.96-0.98）。根据激光类型进行亚组分析，PDL激光的成功率为96% (95% CI: 0.94 ~ 0.973)， Nd:YAG激光的成功率为99% (95% CI: 0.979 ~ 1.008)， 577 nm黄色激光的成功率为86% （95% CI: 0.7621 ~ 0.964）。不同激光类型的并发症发生率PDL为9% (95% CI: 0.031-0.147)， Nd:YAG为4% (95% CI: 0.007-0.080)， 577 nm黄色激光无并发症报道。结论：激光治疗头颈部CMs的绝大多数资料表明，PDL治疗效果好，并发症发生率低。使用Nd:YAG激光治疗的中心报告的成功率略高于PDL或577 nm黄色激光治疗，并发症较少。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Otolaryngology- Head and Neck Surgery 医学-耳鼻喉科学

CiteScore

6.70

自引率

2.90%

发文量

250

审稿时长

2-4 weeks

期刊介绍： Otolaryngology–Head and Neck Surgery (OTO-HNS) is the official peer-reviewed publication of the American Academy of Otolaryngology–Head and Neck Surgery Foundation. The mission of Otolaryngology–Head and Neck Surgery is to publish contemporary, ethical, clinically relevant information in otolaryngology, head and neck surgery (ear, nose, throat, head, and neck disorders) that can be used by otolaryngologists, clinicians, scientists, and specialists to improve patient care and public health.