Eco-Friendly Synthesis of Sesamol-Incorporated Azo Dyes: Anti-Inflammatory Activity and Colourfastness Evaluation

IF 0.8 4区化学 Q4 CHEMISTRY, MULTIDISCIPLINARY

Russian Journal of General Chemistry Pub Date : 2025-05-21 DOI:10.1134/S1070363224610706

J. Raval, B. Patel, V. Patel, B. Dhaduk, J. Lalpara, I. Modasiya, G. Dubal, S. Hadiyal

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Abstract

The negative impacts of synthetic dyes on the environment and health have sparked interest in natural dyes as sustainable and eco-friendly alternatives. We have developed a sustainable method for synthesizing novel sesamol-bearing natural azo dye molecules using water as a solvent. These molecules were tested for their color retention and durability on cotton, linen, and silk materials and showed promising results, indicating their potential application in the textile industry. Furthermore, the synthesized compounds demonstrated significant anti-inflammatory effects, making them potential candidates for pharmaceutical applications. One of the synthesized compounds showed the highest inhibition of 97.30±0.36% against the tested materials. This study highlights the potential of these dye molecules as vibrant coloring agents for textiles and candidates for pharmaceutical applications, with significant inhibitory activity observed in compounds diazotized with different amines.

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芝麻醇偶氮染料的环保合成：抗炎活性和色牢度评价

合成染料对环境和健康的负面影响引发了人们对天然染料作为可持续和环保替代品的兴趣。我们开发了一种以水为溶剂合成含芝麻酚天然偶氮染料分子的可持续方法。这些分子在棉花、亚麻和丝绸材料上测试了它们的保色性和耐久性，并显示出有希望的结果，表明它们在纺织工业中的潜在应用。此外，合成的化合物显示出显著的抗炎作用，使其成为潜在的候选药物应用。其中一种化合物的抑菌率最高，为97.30±0.36%。这项研究强调了这些染料分子作为纺织品和候选药物应用的活力着色剂的潜力，在与不同胺重氮化的化合物中观察到显著的抑制活性。

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来源期刊

Russian Journal of General Chemistry 化学-化学综合

CiteScore

1.40

自引率

22.20%

发文量

252

审稿时长

2-4 weeks

期刊介绍： Russian Journal of General Chemistry is a journal that covers many problems that are of general interest to the whole community of chemists. The journal is the successor to Russia’s first chemical journal, Zhurnal Russkogo Khimicheskogo Obshchestva (Journal of the Russian Chemical Society ) founded in 1869 to cover all aspects of chemistry. Now the journal is focused on the interdisciplinary areas of chemistry (organometallics, organometalloids, organoinorganic complexes, mechanochemistry, nanochemistry, etc.), new achievements and long-term results in the field. The journal publishes reviews, current scientific papers, letters to the editor, and discussion papers.