¹⁸F-FDG PET-CT in patients with prosthetic heart valves: variations in imaging findings: A review of the literature.

IF 3 4区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Journal of Nuclear Cardiology Pub Date : 2025-05-17 DOI:10.1016/j.nuclcard.2025.102247

Eefje M Dalebout, Laurens E Swart, Jolanda Kluin, Annick C Weustink, Ties A Mulders, Jolien W Roos-Hesselink, Alexander Hirsch, Ricardo P J Budde

{"title":"18F-FDG PET-CT in patients with prosthetic heart valves: variations in imaging findings: A review of the literature.","authors":"Eefje M Dalebout, Laurens E Swart, Jolanda Kluin, Annick C Weustink, Ties A Mulders, Jolien W Roos-Hesselink, Alexander Hirsch, Ricardo P J Budde","doi":"10.1016/j.nuclcard.2025.102247","DOIUrl":null,"url":null,"abstract":"Imaging is a cornerstone of the diagnosis of prosthetic valve endocarditis. An abnormal 18F-FDG PET-CT was added as a major diagnostic criterion in the 2015 European Society of Cardiology guidelines for the management of endocarditis. However, interpretation of uptake around prosthetic heart valves (PHVs) can be difficult, because physiological factors and confounders may result in false-positive or false-negative results. This review provides a comprehensive overview of 'normal' uptake by reviewing the literature on uptake surrounding non-infected PHVs. We will elaborate on qualitative and quantitative measures of uptake. Then, differences in uptake between different valve types, implant positions and the natural course of uptake over time following PHV implantation will be discussed. Finally, factors possibly hampering assessment or mimicking infection are reviewed. We aim to support clinical implementation of 18F-FDG PET-CT in suspected prosthetic valve endocarditis and to provide practical guidance to the differentiation between physiological, postoperative and pathological uptake around PHVs.","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":" ","pages":"102247"},"PeriodicalIF":3.0000,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Nuclear Cardiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.nuclcard.2025.102247","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}

引用次数: 0

Abstract

Imaging is a cornerstone of the diagnosis of prosthetic valve endocarditis. An abnormal ¹⁸F-FDG PET-CT was added as a major diagnostic criterion in the 2015 European Society of Cardiology guidelines for the management of endocarditis. However, interpretation of uptake around prosthetic heart valves (PHVs) can be difficult, because physiological factors and confounders may result in false-positive or false-negative results. This review provides a comprehensive overview of 'normal' uptake by reviewing the literature on uptake surrounding non-infected PHVs. We will elaborate on qualitative and quantitative measures of uptake. Then, differences in uptake between different valve types, implant positions and the natural course of uptake over time following PHV implantation will be discussed. Finally, factors possibly hampering assessment or mimicking infection are reviewed. We aim to support clinical implementation of ¹⁸F-FDG PET-CT in suspected prosthetic valve endocarditis and to provide practical guidance to the differentiation between physiological, postoperative and pathological uptake around PHVs.

查看原文本刊更多论文

人工心脏瓣膜患者的18F-FDG PET-CT：影像学表现的变化：文献综述

影像是人工瓣膜心内膜炎诊断的基础。2015年欧洲心脏病学会（European Society of Cardiology）心内膜炎处理指南中增加了18F-FDG PET-CT异常作为主要诊断标准。然而，由于生理因素和混杂因素可能导致假阳性或假阴性结果，解释人工心脏瓣膜（phv）周围的摄取可能很困难。本综述通过回顾有关非感染phv周围摄取的文献，提供了“正常”摄取的全面概述。我们将详细阐述摄取的定性和定量措施。然后，将讨论不同瓣膜类型、植入位置之间的摄取差异以及PHV植入后随时间推移的自然摄取过程。最后，对可能阻碍评估或模拟感染的因素进行了综述。我们的目的是支持18F-FDG PET-CT在疑似人工瓣膜心内膜炎中的临床应用，并为区分phv周围的生理性、术后和病理性摄取提供实用指导。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Nuclear Cardiology 医学-核医学

CiteScore

5.30

自引率

20.80%

发文量

249

审稿时长

4-8 weeks

期刊介绍： Journal of Nuclear Cardiology is the only journal in the world devoted to this dynamic and growing subspecialty. Physicians and technologists value the Journal not only for its peer-reviewed articles, but also for its timely discussions about the current and future role of nuclear cardiology. Original articles address all aspects of nuclear cardiology, including interpretation, diagnosis, imaging equipment, and use of radiopharmaceuticals. As the official publication of the American Society of Nuclear Cardiology, the Journal also brings readers the latest information emerging from the Society''s task forces and publishes guidelines and position papers as they are adopted.