{"title":"mRNA vaccination facilitates the prevention and control of infectious diseases at an unprecedented speed","authors":"Jinmin Ma , Meirong Li , Zhihao Xie , Desheng Li","doi":"10.1016/j.dcit.2025.100048","DOIUrl":null,"url":null,"abstract":"<div><div>In recent years, amidst the progresses of biotechnology versus the emergence and evolution of diseases, the pursuit of mRNA (messenger RNA) vaccines has become a focal point, particularly after their revolutionary function during the COVID-19 pandemic. mRNA vaccines have assumed a pivotal role against infectious diseases, and represent an avenue of exploration that holds great promise. The merits of mRNA vaccines are manifold, and encompass rapid development, unparalleled flexibility and adaptability, the elicitation of potent immune responses, cost-effective manufacturing, and the potential for personalized medicine. The global scientific community has become inspired by the possibilities of expeditious vaccine development, resulting in an extensive tapestry of research and development. However, realizing the full potential of mRNA vaccines is not without scientific and regulatory pitfalls, and necessitates a concerted effort to surmount these challenges. Nevertheless, incremental advances bear testament to the ever-evolving landscape of mRNA vaccine advancement in the battle against COVID-19. We believe that this technology will further play a significant role in the field of infectious diseases. This article aims to describe mRNA vaccine mechanisms and their applications against infectious diseases.</div></div>","PeriodicalId":100358,"journal":{"name":"Decoding Infection and Transmission","volume":"3 ","pages":"Article 100048"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Decoding Infection and Transmission","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2949924025000096","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
In recent years, amidst the progresses of biotechnology versus the emergence and evolution of diseases, the pursuit of mRNA (messenger RNA) vaccines has become a focal point, particularly after their revolutionary function during the COVID-19 pandemic. mRNA vaccines have assumed a pivotal role against infectious diseases, and represent an avenue of exploration that holds great promise. The merits of mRNA vaccines are manifold, and encompass rapid development, unparalleled flexibility and adaptability, the elicitation of potent immune responses, cost-effective manufacturing, and the potential for personalized medicine. The global scientific community has become inspired by the possibilities of expeditious vaccine development, resulting in an extensive tapestry of research and development. However, realizing the full potential of mRNA vaccines is not without scientific and regulatory pitfalls, and necessitates a concerted effort to surmount these challenges. Nevertheless, incremental advances bear testament to the ever-evolving landscape of mRNA vaccine advancement in the battle against COVID-19. We believe that this technology will further play a significant role in the field of infectious diseases. This article aims to describe mRNA vaccine mechanisms and their applications against infectious diseases.