mRNA vaccination facilitates the prevention and control of infectious diseases at an unprecedented speed

Jinmin Ma , Meirong Li , Zhihao Xie , Desheng Li
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Abstract

In recent years, amidst the progresses of biotechnology versus the emergence and evolution of diseases, the pursuit of mRNA (messenger RNA) vaccines has become a focal point, particularly after their revolutionary function during the COVID-19 pandemic. mRNA vaccines have assumed a pivotal role against infectious diseases, and represent an avenue of exploration that holds great promise. The merits of mRNA vaccines are manifold, and encompass rapid development, unparalleled flexibility and adaptability, the elicitation of potent immune responses, cost-effective manufacturing, and the potential for personalized medicine. The global scientific community has become inspired by the possibilities of expeditious vaccine development, resulting in an extensive tapestry of research and development. However, realizing the full potential of mRNA vaccines is not without scientific and regulatory pitfalls, and necessitates a concerted effort to surmount these challenges. Nevertheless, incremental advances bear testament to the ever-evolving landscape of mRNA vaccine advancement in the battle against COVID-19. We believe that this technology will further play a significant role in the field of infectious diseases. This article aims to describe mRNA vaccine mechanisms and their applications against infectious diseases.
mRNA疫苗以前所未有的速度促进了传染病的预防和控制
近年来,随着生物技术的进步和疾病的出现和演变,对mRNA(信使RNA)疫苗的追求成为焦点,特别是在COVID-19大流行期间发挥革命性作用之后。mRNA疫苗在对抗传染病方面发挥了关键作用,并代表着一种具有巨大前景的探索途径。mRNA疫苗的优点是多方面的,包括快速发展,无与伦比的灵活性和适应性,引发强有力的免疫反应,具有成本效益的制造以及个性化医疗的潜力。全球科学界受到迅速研制疫苗的可能性的鼓舞,从而产生了广泛的研究和开发活动。然而,实现mRNA疫苗的全部潜力并非没有科学和监管缺陷,需要共同努力克服这些挑战。然而,这些渐进式的进展证明了mRNA疫苗在抗击COVID-19的斗争中不断发展的前景。我们相信,这项技术将进一步在传染病领域发挥重要作用。本文旨在介绍mRNA疫苗的机制及其在传染病防治中的应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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