Neighbourhood socioeconomic inequality in risk of new-onset asthma associated with an interaction of seven behavioural and psychological factors

IF 3.9 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Public Health Pub Date : 2025-05-21 DOI:10.1016/j.puhe.2025.105752

Bowen Xiang , Mengwei Song , Yuxin Zhang , Quanjun Liu , Qiulin Huang , Qing Wang

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引用次数: 0

Abstract

Objectives

Asthma pertains to both public health and social equality concerns. Yet, the extent to which social inequality is involved in the association of behavioural and psychological factors with new-onset asthma is not clear.

Study design

Cohort study.

Methods

Using the UK Biobank cohort, an interactive measurement for asthma-related behavioural and psychological factors was constructed via Bayesian network-based TOPSIS. The Index of Multiple Deprivation (IMD) measured neighbourhood socioeconomic status. Cox regression assessed the association of behavioural and psychological engagement and IMD with the risk of new-onset asthma, with additive interaction analysis.

Results

During follow-up, 7002 participants were diagnosed with asthma. Obesity contributed most to the network of seven interacted behavioural and psychological factors. Unhealthy behavioural and psychological engagement was associated with a 106 % (HR = 2.06, 95 % CI: 1.91–2.22) increase in the risk of new-onset asthma. The association was most pronounced in the high IMD group, in which the HR of unhealthy behavioural and psychological engagement reached 2.28 (95 % CI: 2.00–2.59). Significant additive interaction (RERI = 0.532, 95 % CI: 0.253–0.812) revealed potential socioeconomic inequality.

Conclusions

Deprived people suffer an additional risk of new-onset asthma associated with the engagement. Coordinating community-level action for socioeconomic improvements and promoting healthy behaviours should be proportionate to the needs.

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社区社会经济不平等对新发哮喘风险的影响与七种行为和心理因素的相互作用有关

目的哮喘涉及公共卫生和社会平等问题。然而，社会不平等在多大程度上涉及行为和心理因素与新发哮喘的关联尚不清楚。研究设计：队列研究。方法利用英国生物银行队列，通过基于贝叶斯网络的TOPSIS构建哮喘相关行为和心理因素的交互测量。多重剥夺指数（IMD）衡量社区的社会经济地位。Cox回归评估了行为和心理参与以及IMD与新发哮喘风险的关联，并进行了加性相互作用分析。结果在随访期间，7002名参与者被诊断患有哮喘。肥胖对七个相互作用的行为和心理因素的影响最大。不健康的行为和心理参与与新发哮喘风险增加106% （HR = 2.06, 95% CI: 1.91-2.22）相关。这种关联在高IMD组中最为明显，其中不健康行为和心理投入的HR达到2.28 （95% CI: 2.00-2.59）。显著的加性相互作用（rei = 0.532, 95% CI: 0.253-0.812）揭示了潜在的社会经济不平等。结论：被剥夺权利的人患新发哮喘的风险与参与相关。协调社区一级改善社会经济和促进健康行为的行动应与需要相称。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Public Health 医学-公共卫生、环境卫生与职业卫生

CiteScore

7.60

自引率

0.00%

发文量

280

审稿时长

37 days

期刊介绍： Public Health is an international, multidisciplinary peer-reviewed journal. It publishes original papers, reviews and short reports on all aspects of the science, philosophy, and practice of public health.