Caroline Chinchilla Putzeys, Trenton House, Janet Iurilli, Ana Gomez, Shipra Garg, Elisa Wershba, Gary Silber, Mitchell Shub, Dana Williams
{"title":"A case of Crohn's disease in a patient with megacystis microcolon intestinal hypoperistalsis syndrome.","authors":"Caroline Chinchilla Putzeys, Trenton House, Janet Iurilli, Ana Gomez, Shipra Garg, Elisa Wershba, Gary Silber, Mitchell Shub, Dana Williams","doi":"10.1002/jpr3.70015","DOIUrl":null,"url":null,"abstract":"<p><p>Megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS) is a rare congenital condition resulting in symptoms of bowel and bladder pseudo-obstruction. It carries severe morbidity and mortality; a minority of patients survive to adulthood. Recurrent bowel surgeries, small intestinal bacterial overgrowth, and slowed intestinal transit in MMIHS could serve as potential risk factors for chronic inflammation of the intestinal mucosa, which has been associated with risk of inflammatory bowel disease. In this case report, we detail the unusual presentation of a patient diagnosed with both MMIHS and inflammatory bowel disease.</p>","PeriodicalId":501015,"journal":{"name":"JPGN reports","volume":"6 2","pages":"184-188"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12078059/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JPGN reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/jpr3.70015","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/5/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS) is a rare congenital condition resulting in symptoms of bowel and bladder pseudo-obstruction. It carries severe morbidity and mortality; a minority of patients survive to adulthood. Recurrent bowel surgeries, small intestinal bacterial overgrowth, and slowed intestinal transit in MMIHS could serve as potential risk factors for chronic inflammation of the intestinal mucosa, which has been associated with risk of inflammatory bowel disease. In this case report, we detail the unusual presentation of a patient diagnosed with both MMIHS and inflammatory bowel disease.