Successful Treatment of a Nonunion Fracture of the Femur With Extracorporeal Shockwave Therapy: An Evidence-Based Case Report.

IF 1 Q3 MEDICINE, GENERAL & INTERNAL
Cureus Pub Date : 2025-05-14 eCollection Date: 2025-05-01 DOI:10.7759/cureus.84138
Theodore Tandiono, Jessica Amelinda Mintarjo, Nunung Nugroho
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Abstract

Nonunion fractures, especially of the femur, pose a considerable difficulty in orthopedic management due to their propensity to result in enduring physical disability and psychological complications. Conventional surgical procedures, although efficacious, may entail difficulties and have a reduced success rate for atrophic nonunions. Extracorporeal shockwave therapy (ESWT) has arisen as a viable non-invasive option, facilitating bone regeneration via many biological mechanisms. This case report describes the management of a 40-year-old male patient with a distal-third open femoral fracture resulting from a motor vehicle accident. Despite receiving open reduction internal fixation and an extensive rehabilitation regimen, the patient had little callus development after six months. ESWT was commenced once weekly for 23 weeks, combined with ultrasonic low-intensity pulsed ultrasound (LIPUS) therapy and leg extension exercises. The patient had full callus formation on the femur and made a full recovery. The comprehensive literature evaluation demonstrates that ESWT can achieve a healing rate of around 73% for nonunion femoral fractures. The therapy's effectiveness is due to its capacity to induce osteogenic responses, promote osteoblast development, and suppress osteoclast production. This non-invasive method diminishes the necessity for supplementary surgical interventions and related complications. Additional research is required to develop standardized methods and refine therapy parameters, guaranteeing consistent and dependable results across various patient groups.

体外冲击波疗法成功治疗股骨不愈合骨折:一例循证病例报告。
骨不连骨折,尤其是股骨骨不连骨折,在骨科治疗中造成了相当大的困难,因为它们往往导致持久的身体残疾和心理并发症。传统的外科手术虽然有效,但对于萎缩性骨不连可能会带来困难和降低成功率。体外冲击波治疗(ESWT)已成为一种可行的非侵入性治疗方法,通过多种生物机制促进骨再生。本病例报告描述了一名40岁男性患者因机动车事故导致股骨远端第三段开放性骨折的处理。尽管接受了切开复位内固定和广泛的康复治疗,患者在6个月后几乎没有出现骨痂。ESWT每周开始一次,持续23周,结合超声低强度脉冲超声(LIPUS)治疗和腿部伸展运动。患者在股骨上形成了完整的骨痂,并完全康复。综合文献评价表明,ESWT治疗股骨骨折不愈合的治愈率约为73%。该疗法的有效性是由于其诱导成骨反应、促进成骨细胞发育和抑制破骨细胞产生的能力。这种非侵入性方法减少了辅助手术干预和相关并发症的必要性。需要进一步的研究来开发标准化的方法和完善治疗参数,以确保在不同的患者群体中获得一致和可靠的结果。
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