Public Attitudes Toward Xenotransplantation in South Korea: A 2023 Survey Study.

IF 3.3 4区医学 Q2 MEDICINE, RESEARCH & EXPERIMENTAL

Xenotransplantation Pub Date : 2025-05-01 DOI:10.1111/xen.70051

Hyeonji Jeon, Jungbeen Lee, Ivo Kwon

{"title":"Public Attitudes Toward Xenotransplantation in South Korea: A 2023 Survey Study.","authors":"Hyeonji Jeon, Jungbeen Lee, Ivo Kwon","doi":"10.1111/xen.70051","DOIUrl":null,"url":null,"abstract":"Background: Xenotransplantation is a promising field to solve the problem of insufficient allograft and has been actively studied in Korea. However, there are a number of ethical, legal, and social issues to consider, and it is necessary to know the public attitudes regarding them.Methods: A Computer Aided Web Interview consisting of 22 questionnaire items was conducted to investigate the attitudes of Korean related to xenotransplantation. Participants were selected from Hankook Research MS (Master Sample) panel. A total of 1007 sets of data were finally collected and analyzed with SPSS. A statistical analysis was performed using an independent t-test and chi-square method.Results: 72.9% of the respondents were positive about xenotransplantation, while 22.2% negative. 61.7% said that they would accept xenotransplantation for incurable diseases. 64.4% agreed with genetically modified pigs for organ resource. 61% agreed that the brain dead could be transplanted first for research purpose, while 32.7% disagreed. The ratio of response that the risk of zoonotic infection is important was 97.2%; the safety issue due to immunosuppression 98.7%; the human identity issue after transplantation 67.4%; and the animal right issue 51.6%. Men were more favorable to xenotransplantation than women on all but one item (stigmatization). There was no significant difference between religions except for the human identity issue.Conclusion: Korean people are favorable to xenotransplantation as a therapeutic option and also positive with the use of pig even genetically modified in spite of the issue of animal rights. They are also positive with the idea of using the brain dead as study subject for xenotransplantation, which is currently forbidden in Korea.","PeriodicalId":23866,"journal":{"name":"Xenotransplantation","volume":"32 3","pages":"e70051"},"PeriodicalIF":3.3000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12087428/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Xenotransplantation","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/xen.70051","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Xenotransplantation is a promising field to solve the problem of insufficient allograft and has been actively studied in Korea. However, there are a number of ethical, legal, and social issues to consider, and it is necessary to know the public attitudes regarding them.

Methods: A Computer Aided Web Interview consisting of 22 questionnaire items was conducted to investigate the attitudes of Korean related to xenotransplantation. Participants were selected from Hankook Research MS (Master Sample) panel. A total of 1007 sets of data were finally collected and analyzed with SPSS. A statistical analysis was performed using an independent t-test and chi-square method.

Results: 72.9% of the respondents were positive about xenotransplantation, while 22.2% negative. 61.7% said that they would accept xenotransplantation for incurable diseases. 64.4% agreed with genetically modified pigs for organ resource. 61% agreed that the brain dead could be transplanted first for research purpose, while 32.7% disagreed. The ratio of response that the risk of zoonotic infection is important was 97.2%; the safety issue due to immunosuppression 98.7%; the human identity issue after transplantation 67.4%; and the animal right issue 51.6%. Men were more favorable to xenotransplantation than women on all but one item (stigmatization). There was no significant difference between religions except for the human identity issue.

Conclusion: Korean people are favorable to xenotransplantation as a therapeutic option and also positive with the use of pig even genetically modified in spite of the issue of animal rights. They are also positive with the idea of using the brain dead as study subject for xenotransplantation, which is currently forbidden in Korea.

查看原文本刊更多论文

韩国公众对异种器官移植的态度：一项2023年的调查研究

背景：异种移植是解决同种异体移植不足问题的一个有前景的领域，在韩国已经得到了积极的研究。然而，有许多伦理、法律和社会问题需要考虑，有必要了解公众对这些问题的态度。方法：采用计算机辅助网络访谈法，对韩国人对异种器官移植的态度进行调查，问卷共22项。参与者是从韩泰研究的MS （Master Sample）小组中挑选出来的。最终共收集1007组数据，并使用SPSS软件进行分析。采用独立t检验和卡方法进行统计分析。结果：72.9%的人对异种器官移植持肯定态度，22.2%的人持否定态度。61.7%的人表示愿意接受异种器官移植治疗不治之症。64.4%的人同意转基因猪作为器官来源。61%的人同意可以先将脑死亡移植用于研究目的，32.7%的人不同意。认为人畜共患感染风险重要的应答率为97.2%；免疫抑制引起的安全性问题占98.7%；移植后人的身份问题67.4%；51.6%的人支持动物权利。男性比女性更支持异种移植，除了一项（污名化）。除了人的身份问题外，宗教之间没有显著差异。结论：虽然存在动物权利问题，但韩国国民对异种器官移植的治疗方案持赞成态度，对转基因猪的使用也持肯定态度。他们对目前在国内被禁止的将脑死亡作为异种器官移植研究对象的想法也持肯定态度。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Xenotransplantation 医学-医学：研究与实验

CiteScore

6.80

自引率

15.40%

发文量

审稿时长

>12 weeks

期刊介绍： Xenotransplantation provides its readership with rapid communication of new findings in the field of organ and tissue transplantation across species barriers.The journal is not only of interest to those whose primary area is xenotransplantation, but also to veterinarians, microbiologists and geneticists. It also investigates and reports on the controversial theological, ethical, legal and psychological implications of xenotransplantation.