68Ga FAPI PET in a Renal Transplant Patient with Disseminated Nocardiosis-A Worthwhile Imaging Modality for Infection Imaging.

IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Nuclear Medicine and Molecular Imaging Pub Date : 2025-06-01 Epub Date: 2024-12-29 DOI:10.1007/s13139-024-00897-8
Srinivas Ananth Kumar, Karthikeyan Subramanian, Bhagwant Rai Mittal, Harmandeep Singh, Rajender Kumar, Sarbpreet Singh
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引用次数: 0

Abstract

Nocardiosis, an opportunistic infection occurs in immunodeficient population commonly in organ transplant recipients. Patients with risk factors likely chronic corticosteroids and immunosuppressants consumption usually have a higher tendency for disseminated infections with formation of deep abscesses at various sites in the body. Functional imaging with PET, being a whole body imaging offers information about the various sites of disease, thereby assisting the treatment planning, treatment response and also to identify the sites of biopsy. 68Ga FAPI PET serves this purpose as previous studies in various other infections have shown activated fibroblasts with increased FAP expression at the infective foci.

68Ga FAPI PET在肾移植患者弥散性诺卡菌病中的应用——一种有价值的感染成像方式。
诺卡菌病是一种机会性感染,常见于器官移植受者的免疫缺陷人群。有长期使用皮质类固醇和免疫抑制剂等危险因素的患者通常更容易发生播散性感染,并在身体各部位形成深部脓肿。PET的功能成像,作为一种全身成像,提供了关于疾病各个部位的信息,从而帮助治疗计划,治疗反应,并确定活检的部位。68Ga FAPI PET具有这一目的,因为先前在各种其他感染中的研究表明,活化的成纤维细胞在感染灶处具有增加的FAP表达。
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来源期刊
Nuclear Medicine and Molecular Imaging
Nuclear Medicine and Molecular Imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
2.20
自引率
7.70%
发文量
58
期刊介绍: Nuclear Medicine and Molecular Imaging (Nucl Med Mol Imaging) is an official journal of the Korean Society of Nuclear Medicine, which bimonthly publishes papers on February, April, June, August, October, and December about nuclear medicine and related sciences such as radiochemistry, radiopharmacy, dosimetry and pharmacokinetics / pharmacodynamics of radiopharmaceuticals, nuclear and molecular imaging analysis, nuclear and molecular imaging instrumentation, radiation biology and radionuclide therapy. The journal specially welcomes works of artificial intelligence applied to nuclear medicine. The journal will also welcome original works relating to molecular imaging research such as the development of molecular imaging probes, reporter imaging assays, imaging cell trafficking, imaging endo(exo)genous gene expression, and imaging signal transduction. Nucl Med Mol Imaging publishes the following types of papers: original articles, reviews, case reports, editorials, interesting images, and letters to the editor. The Korean Society of Nuclear Medicine (KSNM) KSNM is a scientific and professional organization founded in 1961 and a member of the Korean Academy of Medical Sciences of the Korean Medical Association which was established by The Medical Services Law. The aims of KSNM are the promotion of nuclear medicine and cooperation of each member. The business of KSNM includes holding academic meetings and symposia, the publication of journals and books, planning and research of promoting science and health, and training and qualification of nuclear medicine specialists.
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