{"title":"Beyond the usual suspects: A case report of multi-etiological and multidrug-resistant Candida onychomycosis","authors":"Hasti Nouraei , Mehdi Ghahartars , Zahra Zareshahrabadi , Keyvan Pakshir","doi":"10.1016/j.ijmmb.2025.100870","DOIUrl":null,"url":null,"abstract":"<div><div>This is a rare case of <em>Candida</em> onychomycosis caused by three <em>Candida</em> species that were resistant to several antifungal drugs. A 56-year-old Iranian woman with no previous medical or injury history experienced discoloration and lifting of her left thumbnail for six months. Laboratory tests identified yeast and pseudohyphae consistent with <em>Candida</em> onychomycosis. Conventional and molecular techniques confirmed that onychomycosis was caused by three different <em>Candida</em> species. All strains were resistant to various antifungal drugs. Therapeutic failure, in addition to multi-drug resistance, may be due to the presence of multiple etiological agents.</div></div>","PeriodicalId":13284,"journal":{"name":"Indian Journal of Medical Microbiology","volume":"56 ","pages":"Article 100870"},"PeriodicalIF":1.4000,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Medical Microbiology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0255085725000830","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
This is a rare case of Candida onychomycosis caused by three Candida species that were resistant to several antifungal drugs. A 56-year-old Iranian woman with no previous medical or injury history experienced discoloration and lifting of her left thumbnail for six months. Laboratory tests identified yeast and pseudohyphae consistent with Candida onychomycosis. Conventional and molecular techniques confirmed that onychomycosis was caused by three different Candida species. All strains were resistant to various antifungal drugs. Therapeutic failure, in addition to multi-drug resistance, may be due to the presence of multiple etiological agents.
期刊介绍:
Manuscripts of high standard in the form of original research, multicentric studies, meta analysis, are accepted. Current reports can be submitted as brief communications. Case reports must include review of current literature, clinical details, outcome and follow up. Letters to the editor must be a comment on or pertain to a manuscript already published in the IJMM or in relation to preliminary communication of a larger study.
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