The Pre-Analytical Aspects of Blood Gas Analysis Point-Of-Care-Testing (POCT) and Their Impact on Clinical Decision-Making.

IF 0.7 4区医学 Q4 MEDICAL LABORATORY TECHNOLOGY

Clinical laboratory Pub Date : 2025-05-01 DOI:10.7754/Clin.Lab.2024.241029

Siti N A Rahim, Nani Nordin, Hani A Zulkeflee, Wan N F H W Nik, Wan M A W Shuaib, Tuan S T Ismail, Noorazliyana Shafie

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引用次数: 0

Abstract

Background: Laboratory errors can occur during any phase of the total testing process (TTP); however, pre-analytical errors are the most common. Point-of-care testing (POCT) blood gas analysis aids in the reduction of pre-analytical mistakes such as specimen misidentification, analyte degradation, and sample hemolysis caused by analysis delays and vigorous sample handling. Hence, users' understanding of common pre-analytical factors con-founding the results is prudent.

Methods: POCT blood gas has been proven to help allow rapid early diagnosis and triage, better control of mechanical ventilation, safer and reduction in risk of disease transmission, measurements of concurrent electrolytes and acid-base parameters at the bedside, diagnosis of methemoglobinemia and carboxyhemoglobinemia, as well as prompt pre-hospitalized care in remote home care or emergency response settings. However, quality limitations are still a concerning issue.

Results: Thus, the successful implementation of policy and clinical applicability of blood gas POCT is the responsibility of primary healthcare givers, laboratory professionals, and administrators.

Conclusions: Our review highlights the importance of understanding pre-analytical factors affecting parameters in blood gas analysis, their impact on clinical decision-making, and various POCT blood gas analysis applications.

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血气分析护理点检测（POCT）的前分析方面及其对临床决策的影响。

背景：实验室错误可能发生在整个检测过程（TTP）的任何阶段；然而，分析前错误是最常见的。即时检测（POCT）血气分析有助于减少分析前的错误，如样品错误鉴定，分析物降解，以及由分析延迟和有力的样品处理引起的样品溶血。因此，用户对混淆结果的常见分析前因素的理解是谨慎的。方法：POCT血气已被证明有助于快速早期诊断和分类，更好地控制机械通气，更安全和降低疾病传播风险，在床边同时测量电解质和酸碱参数，诊断高铁血红蛋白血症和羧血红蛋白血症，以及在远程家庭护理或紧急响应环境中及时进行院前护理。然而，质量限制仍然是一个令人担忧的问题。结果：因此，血气POCT政策的成功实施和临床适用性是初级卫生保健提供者、实验室专业人员和管理人员的责任。结论：我们的综述强调了了解影响血气分析参数的分析前因素、它们对临床决策的影响以及各种POCT血气分析应用的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical laboratory 医学-医学实验技术

CiteScore

1.50

自引率

0.00%

发文量

494

审稿时长

3 months

期刊介绍： Clinical Laboratory is an international fully peer-reviewed journal covering all aspects of laboratory medicine and transfusion medicine. In addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies. The journal publishes original articles, review articles, posters, short reports, case studies and letters to the editor dealing with 1) the scientific background, implementation and diagnostic significance of laboratory methods employed in hospitals, blood banks and physicians'' offices and with 2) scientific, administrative and clinical aspects of transfusion medicine and 3) in addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies.