{"title":"Impact of Micronutrients and Macronutrients on NK Cells Immunity.","authors":"Thamer A Hamdan","doi":"10.33594/000000776","DOIUrl":null,"url":null,"abstract":"<p><p>Natural killer (NK) cells are cytotoxic lymphocytes of the innate immune system. Along with their cardinal role in eliminating virally infected and cancerous cells, they are considered as a bridge between innate and adaptive immunity. Nutrition is linked to the effective immune response, and it is known that nutrition is among the environmental factors that influence the immune function and physiology. The function of nutrients, which are dissected into micronutrients (e.g. vitamins and minerals) and macronutrients (e.g. fat, protein and carbohydrates), is to maintain the metabolism and energy which are prime to fuel NK cells. In this review, we are going to recapitulate the recent findings and available data regarding the effect of common micro and macronutrients` examples on the NK cells development and function to provide an insight into diet-immune system crosstalk.</p>","PeriodicalId":9845,"journal":{"name":"Cellular Physiology and Biochemistry","volume":"59 3","pages":"313-329"},"PeriodicalIF":2.5000,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cellular Physiology and Biochemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33594/000000776","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CELL BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Natural killer (NK) cells are cytotoxic lymphocytes of the innate immune system. Along with their cardinal role in eliminating virally infected and cancerous cells, they are considered as a bridge between innate and adaptive immunity. Nutrition is linked to the effective immune response, and it is known that nutrition is among the environmental factors that influence the immune function and physiology. The function of nutrients, which are dissected into micronutrients (e.g. vitamins and minerals) and macronutrients (e.g. fat, protein and carbohydrates), is to maintain the metabolism and energy which are prime to fuel NK cells. In this review, we are going to recapitulate the recent findings and available data regarding the effect of common micro and macronutrients` examples on the NK cells development and function to provide an insight into diet-immune system crosstalk.
期刊介绍：
Cellular Physiology and Biochemistry is a multidisciplinary scientific forum dedicated to advancing the frontiers of basic cellular research. It addresses scientists from both the physiological and biochemical disciplines as well as related fields such as genetics, molecular biology, pathophysiology, pathobiochemistry and cellular toxicology & pharmacology. Original papers and reviews on the mechanisms of intracellular transmission, cellular metabolism, cell growth, differentiation and death, ion channels and carriers, and the maintenance, regulation and disturbances of cell volume are presented. Appearing monthly under peer review, Cellular Physiology and Biochemistry takes an active role in the concerted international effort to unravel the mechanisms of cellular function.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
