Effects of concentrated growth factor combined with Bio-Oss bone powder on guided bone regeneration in the maxillary posterior region.

IF 1.6 4区医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL

American journal of translational research Pub Date : 2025-04-15 eCollection Date: 2025-01-01 DOI:10.62347/LGVQ8407

Zhe Cheng, Yili Pan, Qin Pan

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引用次数: 0

Abstract

Objective: To evaluate the clinical effects of concentrated growth factor (CGF) combined with Bio-Oss bone powder on guided bone regeneration for the maxillary posterior region.

Methods: This retrospective study included 32 patients with missing maxillary posterior teeth and severe alveolar ridge atrophy requiring implant restoration for retrospective analysis. Sixteen patients received CGF combined with Bio-Oss treatment (CGF/Bio group), while the remaining 16 received Bio-Oss treatment only (Bio group). The Bio group used Bio-Oss bone powder directly. Cone-beam computed tomography (CBCT) was performed preoperatively and at 2, 4, and 6 months postoperatively to evaluate bone mineral density (HU values). The implant retention rate, soft tissue healing time, postoperative pain, and swelling were also evaluated.

Results: The 1-year implant retention rate was 100% in the CGF/Bio group and 81.25% in the Bio group (P = 0.054). Soft tissue healing time was significantly shorter in the CGF/Bio group (P = 0.122). Bone density was significantly higher in the CGF/Bio group at 2, 4, and 6 months postoperatively (P < 0.05). Postoperative pain and swelling were significantly lower in the CGF/Bio group (P = 0.008 and P = 0.014, respectively).

Conclusion: The combined application of CGF and Bio-Oss bone powder in maxillary sinus external lift demonstrates superior clinical outcomes, offering improved bone augmentation and enhanced postoperative healing compared to Bio-Oss bone powder alone.

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浓缩生长因子联合Bio-Oss骨粉对上颌后牙区引导骨再生的影响。

目的：评价浓缩生长因子（CGF）联合Bio-Oss骨粉在上颌后牙区引导骨再生中的临床效果。方法：回顾性分析32例上颌后牙缺失和严重牙槽嵴萎缩需要种植体修复的患者。16例患者接受CGF联合Bio- oss治疗（CGF/Bio组），其余16例患者仅接受Bio- oss治疗（Bio组）。Bio组直接使用Bio- oss骨粉。术前及术后2、4、6个月行锥形束计算机断层扫描（CBCT）评估骨矿物质密度（HU值）。同时评估种植体保留率、软组织愈合时间、术后疼痛和肿胀。结果：CGF/Bio组1年种植体固位率为100%，Bio组为81.25% （P = 0.054）。CGF/Bio组软组织愈合时间明显缩短（P = 0.122）。CGF/Bio组术后2、4、6个月骨密度显著高于对照组（P < 0.05）。CGF/Bio组术后疼痛和肿胀明显减轻（P = 0.008和P = 0.014）。结论：CGF与Bio-Oss骨粉联合应用于上颌窦外提术具有较好的临床效果，与单独应用Bio-Oss骨粉相比，具有更好的骨增强效果和术后愈合能力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American journal of translational research ONCOLOGY-MEDICINE, RESEARCH & EXPERIMENTAL

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552

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