Continuous glucose monitoring: Minimally and non-invasive technologies

IF 3.2 3区 医学 Q2 MEDICAL LABORATORY TECHNOLOGY
Jeong Eun Lee , Badrinathan Sridharan , Daehun Kim , Yeongho Sung , Jin Hyeong Park , Hae Gyun Lim
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Abstract

This paper highlights technological advancements in non-invasive blood glucose monitoring against the backdrop of increasing global prevalence of diabetes. Traditional monitoring methods, primarily invasive methods face limitations in providing continuous glucose level data, which is essential for effective and timely diagnosis of disease stage and for determining the optimal therapeutic strategy. Recent non-invasive technologies encompass optical, acoustic, electromagnetic, and chemical approaches. These technologies exploit the intrinsic properties of glucose, such as its optical absorption coefficients, to offer promising avenues for less intrusive blood glucose monitoring. Despite these advancements, challenges in achieving high accuracy persist due to interference from substances like water and other blood components. This underlines the need for sophisticated algorithms and sensor designs for accurate glucose estimation. Further research is required to integrate various sensing techniques and advanced data processing to enhance accuracy and user-friendliness. In conclusion, while significant progress has been made, developing a reliable, convenient, and accessible method for non-invasive glucose monitoring is crucial for transforming diabetes management and improving patients’ quality of life.
连续血糖监测:微创和无创技术
本文重点介绍了在全球糖尿病患病率不断上升的背景下,无创血糖监测的技术进展。传统的监测方法,主要是侵入性方法,在提供连续的血糖水平数据方面存在局限性,而血糖水平数据对于有效及时地诊断疾病阶段和确定最佳治疗策略至关重要。最近的非侵入性技术包括光学、声学、电磁和化学方法。这些技术利用葡萄糖的固有特性,如其光学吸收系数,为低侵入性血糖监测提供了有希望的途径。尽管取得了这些进步,但由于水和其他血液成分等物质的干扰,实现高精度的挑战仍然存在。这强调需要复杂的算法和传感器设计准确的葡萄糖估计。需要进一步的研究来整合各种传感技术和先进的数据处理,以提高准确性和用户友好性。总之,在取得重大进展的同时,开发一种可靠、方便、可及的无创血糖监测方法对于改变糖尿病管理和提高患者生活质量至关重要。
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来源期刊
Clinica Chimica Acta
Clinica Chimica Acta 医学-医学实验技术
CiteScore
10.10
自引率
2.00%
发文量
1268
审稿时长
23 days
期刊介绍: The Official Journal of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) Clinica Chimica Acta is a high-quality journal which publishes original Research Communications in the field of clinical chemistry and laboratory medicine, defined as the diagnostic application of chemistry, biochemistry, immunochemistry, biochemical aspects of hematology, toxicology, and molecular biology to the study of human disease in body fluids and cells. The objective of the journal is to publish novel information leading to a better understanding of biological mechanisms of human diseases, their prevention, diagnosis, and patient management. Reports of an applied clinical character are also welcome. Papers concerned with normal metabolic processes or with constituents of normal cells or body fluids, such as reports of experimental or clinical studies in animals, are only considered when they are clearly and directly relevant to human disease. Evaluation of commercial products have a low priority for publication, unless they are novel or represent a technological breakthrough. Studies dealing with effects of drugs and natural products and studies dealing with the redox status in various diseases are not within the journal''s scope. Development and evaluation of novel analytical methodologies where applicable to diagnostic clinical chemistry and laboratory medicine, including point-of-care testing, and topics on laboratory management and informatics will also be considered. Studies focused on emerging diagnostic technologies and (big) data analysis procedures including digitalization, mobile Health, and artificial Intelligence applied to Laboratory Medicine are also of interest.
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