Artritis psoriásica

Abstract

Psoriatic arthritis (PsA) is a chronic inflammatory disease that can affect joints, tendons, entheses, and the axial skeleton. It usually occurs in patients with psoriasis. It is a complex, multifactorial disease favored by genetic, environmental, and immunological factors, among which TNF-alpha, IL-23, and IL-17 are the most important. There are no validated diagnostic criteria for PsA, but the CASPAR (ClASsification criteria for Psoriatic Arthritis) criteria can serve as a guide in clinical practice. In addition to joint manifestations, patients may present with extramusculoskeletal manifestations and comorbidities that must be taken into account in the management of the disease. Conventional, biological, or synthetic disease-modifying antirheumatic drugs (DMARDs) are available for its treatment.