Effects of Replacing Intradialytic Parenteral Nutrition by Oral Nutritional Supplements and Polyester-Polyarylate Membrane on Nutritional Status in Maintenance Hemodialysis Patients with End-Stage Kidney Disease.

Biomedicine hub Pub Date : 2025-04-03 eCollection Date: 2025-01-01 DOI:10.1159/000545460

Maxime Hoffmann, Amaury Ben Henda, Omar Mazouz, Rachid Amaria

{"title":"Effects of Replacing Intradialytic Parenteral Nutrition by Oral Nutritional Supplements and Polyester-Polyarylate Membrane on Nutritional Status in Maintenance Hemodialysis Patients with End-Stage Kidney Disease.","authors":"Maxime Hoffmann, Amaury Ben Henda, Omar Mazouz, Rachid Amaria","doi":"10.1159/000545460","DOIUrl":null,"url":null,"abstract":"Introduction: In patients receiving hemodialysis, protein-energy wasting may be frequent and is associated with nutritional and metabolic alterations. This study aimed to describe the effects of a new therapeutic strategy, i.e., oral nutritional supplements (ONS) associated with a polyester-polyarylate (PEPA) membrane, on nutritional markers in high-risk patients with intradialytic parenteral nutrition (IDPN) history.Methods: Patients, who received individually IDPN (M-6 to M0) then ONS (M0 to M6), were followed over a 12-month period.Results: There was no change in serum albumin over time. The BMI increased between M-6 and M6. Food intake showed increase between M0 and M3. Quality-of-life score was stable between M0 and M6. None of the adverse events was judged related to ONS, PEPA, or research procedure.Conclusion: This study focusing on a new therapeutic strategy composed of ONS and PEPA membrane replacing IDPN to maintain nutritional markers in high-risk patients receiving hemodialysis might warrant further research with robust methodology.","PeriodicalId":101351,"journal":{"name":"Biomedicine hub","volume":"10 1","pages":"98-104"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077863/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedicine hub","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000545460","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Introduction: In patients receiving hemodialysis, protein-energy wasting may be frequent and is associated with nutritional and metabolic alterations. This study aimed to describe the effects of a new therapeutic strategy, i.e., oral nutritional supplements (ONS) associated with a polyester-polyarylate (PEPA) membrane, on nutritional markers in high-risk patients with intradialytic parenteral nutrition (IDPN) history.

Methods: Patients, who received individually IDPN (M-6 to M0) then ONS (M0 to M6), were followed over a 12-month period.

Results: There was no change in serum albumin over time. The BMI increased between M-6 and M6. Food intake showed increase between M0 and M3. Quality-of-life score was stable between M0 and M6. None of the adverse events was judged related to ONS, PEPA, or research procedure.

Conclusion: This study focusing on a new therapeutic strategy composed of ONS and PEPA membrane replacing IDPN to maintain nutritional markers in high-risk patients receiving hemodialysis might warrant further research with robust methodology.

查看原文本刊更多论文

口服营养补充剂和聚酯-聚芳烃膜对终末期肾病维持性血液透析患者营养状况的影响

在接受血液透析的患者中，蛋白质能量浪费可能是频繁的，并且与营养和代谢改变有关。本研究旨在描述一种新的治疗策略，即口服营养补充剂（ONS）与聚酯-聚芳酸酯（PEPA）膜，对有分析性肠外营养（IDPN）史的高危患者的营养标志物的影响。方法：分别接受IDPN （M-6 ~ M0）和ONS （M0 ~ M6）治疗的患者，随访12个月。结果：血清白蛋白无明显变化。BMI在M-6和M6之间增加。食物摄取量在M0和M3之间呈增加趋势。生活质量评分稳定在M0 ~ M6之间。没有任何不良事件被认为与ONS、PEPA或研究程序有关。结论：本研究关注的是由ONS和PEPA膜代替IDPN维持高危血液透析患者营养标志物的新治疗策略，可能值得进一步研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Biomedicine hub

自引率

0.00%

发文量