Exploring Polypharmacy in the BC Correctional Health Setting.

The Canadian journal of hospital pharmacy Pub Date : 2025-05-14 eCollection Date: 2025-01-01 DOI:10.4212/cjhp.3708
Lillian Lo, Sarah Masson, Matthew Brons, Benjamin Leung
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Abstract

Background: Greater burdens of comorbidity and exposure to unique environmental factors predispose incarcerated individuals to polypharmacy and inappropriate prescribing. There is limited literature investigating polypharmacy within the correctional health setting.

Objectives: To determine the median number of medications prescribed per client at facilities in British Columbia, to determine the proportion of clients meeting the definition for polypharmacy, to identify the top medication categories prescribed, and to screen for potential drug therapy problems among those with polypharmacy.

Methods: An observational point prevalence study of adult clients with one or more active medications on the census date at 5 correctional health facilities in British Columbia was conducted. Clients were excluded if they had one-time or no medication orders on the census date.

Results: Of the 500 clients screened, 420 were included in the final analysis. Across the centres, the median number of medications ranged from 3 to 5 per client, and the rate of polypharmacy ranged from 23% to 41%. Of the scheduled medications, opioid agonist therapy and psychotropics were the leading categories prescribed across all facilities. Non-opioid analgesics were the top "as needed" medications prescribed at 4 of the 5 facilities. The leading potential drug therapy problem identified was drug interactions resulting in additive sedation.

Conclusions: Polypharmacy was present within all facilities in this study, with more than 25% of clients affected at 3 of the sites. The top medications prescribed aligned with those identified in the literature; however, there remain opportunities for therapy optimization.

探索不列颠哥伦比亚省惩教卫生环境中的综合药房。
背景:更大的合并症负担和暴露于独特的环境因素使被监禁者易患多种药物和不适当的处方。在惩教卫生环境中调查多种药物的文献有限。目的:确定在不列颠哥伦比亚省的设施中,每个病人的药物处方中位数,确定符合多药定义的病人的比例,确定处方的最高药物类别,并筛选多药患者中潜在的药物治疗问题。方法:对不列颠哥伦比亚省5个惩教卫生机构在人口普查日期使用一种或多种有效药物的成年客户进行观察点患病率研究。如果客户在人口普查日期有一次性或没有药物订单,则被排除在外。结果:在筛选的500名客户中,420名被纳入最终分析。在各个中心,每个病人的药物中位数从3到5不等,多种药物使用率从23%到41%不等。在预定的药物中,阿片类激动剂治疗和精神药物是所有机构开出的主要类别。非阿片类镇痛药是5家机构中4家开出的“按需”用药最多的药物。确定的主要潜在药物治疗问题是药物相互作用导致附加镇静。结论:本研究中所有医院都存在多药现象,其中3家医院超过25%的患者受到影响。处方的顶级药物与文献中确定的药物一致;然而,仍有机会进行治疗优化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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