Anatomical Feasibility of a Thoracic Branched Endograft for Aortic Pathology Requiring Proximal Sealing in Zone 2.

IF 5.7 1区 医学 Q1 PERIPHERAL VASCULAR DISEASE
Andrea Vacirca, Gianluca Faggioli, Stefania Caputo, Antonino Di Leo, Enrico Gallitto, Mauro Gargiulo
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引用次数: 0

Abstract

Objective: Type B acute aortic syndrome (AAS) and thoracic or thoraco-abdominal aortic aneurysm (TAA/TAAA) requiring proximal sealing in Ishimaru zone 2 have traditionally been managed with thoracic endovascular aortic repair (T-EVAR), often combined with carotid-subclavian bypass. The new Gore Thoracic Branch Endograft (TBE) facilitates the treatment of distal aortic arch lesions by including the left subclavian artery yet maintaining its patency. This study aimed to assess the anatomical feasibility of TBE in patients treated or awaiting treatment for AAS or TAA/TAAA requiring proximal seal in zone 2.

Methods: This was a retrospective cohort analysis of all patients with AAS or TAA/TAAA referred to a single centre (January 2018 to March 2025) requiring proximal seal in zone 2 and with an indication for endovascular repair. Pre-operative computed tomography scans were reviewed. Anatomical feasibility (AF) was defined according to the TBE instructions for use. Iliac feasibility (IF) was determined based on iliofemoral diameters and calcification. True feasibility (TF) was the combination of AF and IF.

Results: During the study period, 93 patients (78% male; median age at presentation 72 years [interquartile range 16]) were enrolled, of whom 65 (70%) had AAS and 28 (30%) had TAA/TAAA. T-EVAR with CSB was performed in 53% (49/93), T-EVAR with LSA coverage in 26% (24/93), and TBE in 5% (5/93); 16% (15/93) were awaiting endovascular repair. The overall AF for TBE was 92%, while TF was 85%, with seven patients showing hostile iliofemoral axes. There were no statistically significant differences in TBE AF (AAS 91% vs. TAA/TAAA 96%; p = .67) and TF (AAS 85% vs. TAA/TAAA 86%; p = 1.0) among patients with AAS and TAA/TAAA.

Conclusion: TBE showed high AF in both AAS and TAA/TAAAs requiring proximal sealing in zone 2. However, the elevated profile of the endograft may be considered a concern in patients with hostile iliofemoral axes.

需要近端封闭主动脉2区的胸支内移植术的解剖学可行性。
目的:B型急性主动脉综合征(AAS)和胸或胸腹主动脉瘤(TAA/TAAA)在Ishimaru 2区需要近端封闭,传统上采用胸血管内主动脉修复(T-EVAR)治疗,通常联合颈动脉-锁骨下搭桥。新的Gore胸椎分支内移植物(TBE)通过包括左锁骨下动脉并保持其通畅,促进了主动脉弓远端病变的治疗。本研究旨在评估治疗或等待治疗AAS或TAA/TAAA需要近端2区封闭的患者进行TBE的解剖学可行性。方法:这是一项回顾性队列分析,纳入了2018年1月至2025年3月在单一中心就诊的所有AAS或TAA/TAAA患者,这些患者需要近端封闭2区,并有血管内修复的指征。回顾术前计算机断层扫描。解剖可行性(AF)根据TBE使用说明书进行定义。髂可行性(IF)根据髂股直径和钙化情况确定。真实可行性(TF)是AF和IF的组合。结果:研究期间,93例患者(男性78%;入院时中位年龄72岁[四分位数差16]),其中65例(70%)患有AAS, 28例(30%)患有TAA/TAAA。T-EVAR合并CSB的覆盖率为53% (49/93),T-EVAR合并LSA的覆盖率为26% (24/93),TBE覆盖率为5% (5/93);16%(15/93)等待血管内修复。TBE的总体AF为92%,而TF为85%,其中7例患者表现为髂股轴不友好。两组间的房颤差异无统计学意义(AAS 91% vs TAA/TAAA 96%;p = .67)和TF (AAS 85% vs. TAA/TAAA 86%;p = 1.0)。结论:AAS和TAA/TAAAs均表现为高AF,需要近端2区封闭。然而,对于髂股轴不友好的患者,内移植物的高轮廓可能被认为是一个问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.80
自引率
15.80%
发文量
471
审稿时长
66 days
期刊介绍: The European Journal of Vascular and Endovascular Surgery is aimed primarily at vascular surgeons dealing with patients with arterial, venous and lymphatic diseases. Contributions are included on the diagnosis, investigation and management of these vascular disorders. Papers that consider the technical aspects of vascular surgery are encouraged, and the journal includes invited state-of-the-art articles. Reflecting the increasing importance of endovascular techniques in the management of vascular diseases and the value of closer collaboration between the vascular surgeon and the vascular radiologist, the journal has now extended its scope to encompass the growing number of contributions from this exciting field. Articles describing endovascular method and their critical evaluation are included, as well as reports on the emerging technology associated with this field.
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