{"title":"Local Control in Soft Tissue Sarcomas.","authors":"Elizabeth H Baldini, Alessandro Gronchi","doi":"10.1016/j.hoc.2025.04.011","DOIUrl":null,"url":null,"abstract":"<p><p>Soft tissue sarcoma is a rare heterogeneous group of tumors made up of over 100 histologic types and subtypes. Expert pathology review is crucial to confirm the correct diagnosis prior to treatment. Multidisciplinary discussion and management at an expert center is strongly recommended given the many nuances of treatment. Wide resection +/- preoperative radiotherapy is recommended in most extremity and trunk wall STS patients, while a minority may also require perioperative medical therapy. Macroscopic complete resection remains the standard of care for retroperitoneal sarcoma patients, with preoperative radiotherapy recommended in selected histologic types.</p>","PeriodicalId":55060,"journal":{"name":"Hematology-Oncology Clinics of North America","volume":" ","pages":""},"PeriodicalIF":2.5000,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hematology-Oncology Clinics of North America","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.hoc.2025.04.011","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"HEMATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Soft tissue sarcoma is a rare heterogeneous group of tumors made up of over 100 histologic types and subtypes. Expert pathology review is crucial to confirm the correct diagnosis prior to treatment. Multidisciplinary discussion and management at an expert center is strongly recommended given the many nuances of treatment. Wide resection +/- preoperative radiotherapy is recommended in most extremity and trunk wall STS patients, while a minority may also require perioperative medical therapy. Macroscopic complete resection remains the standard of care for retroperitoneal sarcoma patients, with preoperative radiotherapy recommended in selected histologic types.
期刊介绍:
Hematology/Oncology Clinics updates you on the latest trends in patient management, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Under the direction of an experienced guest editor, each issue focuses on a single topic in hematology and oncology, including hemostasis and thrombosis, molecular and cellular basis of hematology, coagulation disorders, and cancers—bone, gastrointestinal, head and neck, lymphomas, neuroendocrine, breast, renal cell, melanoma, and more.