Ewing Sarcoma, Desmoplastic Small Round Cell Tumor, and Other Round Cell Sarcomas.

IF 2.5 3区医学 Q2 HEMATOLOGY

Hematology-Oncology Clinics of North America Pub Date : 2025-05-14 DOI:10.1016/j.hoc.2025.04.003

M Jane Underdown, Sarah Kappa, Jonathan Metts, Thomas Cash

引用次数: 0

Abstract

The classification of small round cell sarcomas encompasses a spectrum of diseases ranging from those that are more widely understood, such as Ewing sarcoma and desmoplastic small round cell tumor, to more newly characterized diseases such as capicua (CIC)-rearranged sarcomas, BCOR-altered sarcomas, and sarcomas with EWSR1-non-ETS fusions. This article provides background, unique molecular features, and current and emerging therapies for each round cell sarcoma subtype.

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尤文氏肉瘤、结缔组织增生小圆细胞瘤和其他圆细胞肉瘤。

小圆细胞肉瘤的分类涵盖了一系列疾病，从那些更广为人知的疾病，如尤文氏肉瘤和促结缔组织增生小圆细胞瘤，到更多新发现的疾病，如capicua （CIC）重排肉瘤、bcr改变的肉瘤和ewsr1 -非ets融合的肉瘤。本文提供了背景，独特的分子特征，以及当前和新兴的治疗每个圆形细胞肉瘤亚型。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Hematology-Oncology Clinics of North America 医学-血液学

CiteScore

4.10

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Hematology/Oncology Clinics updates you on the latest trends in patient management, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Under the direction of an experienced guest editor, each issue focuses on a single topic in hematology and oncology, including hemostasis and thrombosis, molecular and cellular basis of hematology, coagulation disorders, and cancers—bone, gastrointestinal, head and neck, lymphomas, neuroendocrine, breast, renal cell, melanoma, and more.