Dynamic morphofunctional characteristics of the respiratory tract in children with recurrent respiratory diseases depending on the method of therapy.

Abstract

Objective: Aim: To investigate the data of the morphofunctional study of the respiratory tract in children with recurrent respiratory diseases in dynamics, depending on the method of therapy.

Patients and methods: Materials and Methods: The study included 118 children of primary school age with a diagnosis of recurrent respiratory diseases and 26 healthy children identical in age, gender and anthropometric parameters. Two study groups were created, depending on the treatment method: group 1 - 62 patients (optimized therapy,OT), group 2 - 56 patients (basic therapy,BT).

Results: Results: Significant differences after treatment were observed in following spirogram indicators: FVC (%) at p1<0,01, p3=0,008 in the OT group; FEV1 (%) at p1=0,001, p3=0,01 in the group with OT; PEF (%) at p1=0,02 in the group of children of OT and p4=0,006 in the group of children of BT; MEF 25 (%) with p1=0,03, p3=0,05 in the group of OT children and p4=0,01 in the group of BT children; Tifno index (%) at p4=0,002, p6=0,01, р7=0,02 with significant changes between the data on OT and BT groups; MEF 50 (%) at р7=0,01 with a significant prevalence of OT data (by 1,2 times) against BT data.

Conclusion: Conclusions: The obtained data allow us to say that the addition of vitamin-mineral complex drugs to the standard treatment regimen has a positive effect on the state of the respiratory system in children with a diagnosis of recurrent respiratory diseases.