Gastric cancer treatment in Brazil: a multicenter study of the Brazilian Gastric Cancer Association.

Revista do Colegio Brasileiro de Cirurgioes Pub Date : 2025-05-12 eCollection Date: 2025-01-01 DOI:10.1590/0100-6991e-20253815_en

Marcus Fernando Kodama Pertille Ramos, Marina Alessandra Pereira, Thiago Francischetto Ribeiro, Oddone Braghiroli Neto, Felipe José Fernandez Coimbra, Marco Antônio Gonçalves Rodrigues, Flavio Duarte Sabino, Ulysses Ribeiro Junior, Ronaldo Mafia Cuenca, Felipe Carvalho Victer, Flávio Daniel Saavedra Tomasich, Geraldo Ishak, Antonio Nocchi Kalil, Álvaro Antônio Bandeira Ferraz, Luis Fernando Moreira, Claudemiro Quireze Junior, Nelson Adami Andreollo, Osvaldo Antônio Prado Castro, Fernando Antônio Siqueira Pinheiro, Antônio Carlos Weston

{"title":"Gastric cancer treatment in Brazil: a multicenter study of the Brazilian Gastric Cancer Association.","authors":"Marcus Fernando Kodama Pertille Ramos, Marina Alessandra Pereira, Thiago Francischetto Ribeiro, Oddone Braghiroli Neto, Felipe José Fernandez Coimbra, Marco Antônio Gonçalves Rodrigues, Flavio Duarte Sabino, Ulysses Ribeiro Junior, Ronaldo Mafia Cuenca, Felipe Carvalho Victer, Flávio Daniel Saavedra Tomasich, Geraldo Ishak, Antonio Nocchi Kalil, Álvaro Antônio Bandeira Ferraz, Luis Fernando Moreira, Claudemiro Quireze Junior, Nelson Adami Andreollo, Osvaldo Antônio Prado Castro, Fernando Antônio Siqueira Pinheiro, Antônio Carlos Weston","doi":"10.1590/0100-6991e-20253815_en","DOIUrl":null,"url":null,"abstract":"Introduction: Gastric cancer (GC) has distinct characteristics and management according to the region of the world, and the objective of our study was to evaluate how it is being managed in Brazil.Methods: This is a multicenter study that involved 18 oncology referral centers. Data were collected using the REDCap platform and compiled at the end of one year.Results: All Brazilian regions were represented, and 635 patients were included. Most patients were from the Southeast (40.6%) and Northeast (29.6%) regions. The mean age was 62 years, with a predominance of males. Most patients (84.6%) had good performance status, with an ECOG score of 1-2. Less than 10% of patients were covered by medical insurance. A quarter of the patients underwent diagnostic laparoscopy, but endoscopic ultrasound and PET scans were rarely performed. The cT3 category was the most common (40.6%), lymph node involvement was described in 48.9%, and distant metastases, in 14.4% of the staging exams. The final cTNM staging was III (29.4%), II (26%), I (24.2%) and IV (20.5%). Most patients underwent surgery with curative intent (74.4%) and open access (82.8%). Preoperative chemotherapy was performed in 37.2% of cases, and the most common surgical procedures were subtotal gastrectomy (45.3%) and total gastrectomy (33.1%).Conclusion: The present study allowed us to evaluate the current panorama of surgical treatment of Gastric Cancer, representing all regions of Brazil. Stage III, distal, and diffuse tumors continue to be prevalent in Brazil, and there has been relevant use of diagnostic laparoscopy, preoperative chemotherapy, and minimally invasive surgery.","PeriodicalId":21454,"journal":{"name":"Revista do Colegio Brasileiro de Cirurgioes","volume":"52 ","pages":"e20253815"},"PeriodicalIF":0.0000,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12037263/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista do Colegio Brasileiro de Cirurgioes","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1590/0100-6991e-20253815_en","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Introduction: Gastric cancer (GC) has distinct characteristics and management according to the region of the world, and the objective of our study was to evaluate how it is being managed in Brazil.

Methods: This is a multicenter study that involved 18 oncology referral centers. Data were collected using the REDCap platform and compiled at the end of one year.

Results: All Brazilian regions were represented, and 635 patients were included. Most patients were from the Southeast (40.6%) and Northeast (29.6%) regions. The mean age was 62 years, with a predominance of males. Most patients (84.6%) had good performance status, with an ECOG score of 1-2. Less than 10% of patients were covered by medical insurance. A quarter of the patients underwent diagnostic laparoscopy, but endoscopic ultrasound and PET scans were rarely performed. The cT3 category was the most common (40.6%), lymph node involvement was described in 48.9%, and distant metastases, in 14.4% of the staging exams. The final cTNM staging was III (29.4%), II (26%), I (24.2%) and IV (20.5%). Most patients underwent surgery with curative intent (74.4%) and open access (82.8%). Preoperative chemotherapy was performed in 37.2% of cases, and the most common surgical procedures were subtotal gastrectomy (45.3%) and total gastrectomy (33.1%).

Conclusion: The present study allowed us to evaluate the current panorama of surgical treatment of Gastric Cancer, representing all regions of Brazil. Stage III, distal, and diffuse tumors continue to be prevalent in Brazil, and there has been relevant use of diagnostic laparoscopy, preoperative chemotherapy, and minimally invasive surgery.

查看原文本刊更多论文

巴西胃癌治疗：巴西胃癌协会的一项多中心研究

导论：胃癌（GC）在世界不同地区有不同的特点和治疗方法，本研究的目的是评估巴西的胃癌治疗方法。方法：这是一项涉及18个肿瘤转诊中心的多中心研究。使用REDCap平台收集数据，并在一年底进行汇编。结果：巴西所有地区均有纳入，共纳入635例患者。患者主要来自东南部（40.6%）和东北部（29.6%）地区。平均年龄62岁，男性居多。大多数患者（84.6%）表现良好，ECOG评分为1-2分。只有不到10%的病人有医疗保险。四分之一的患者接受了诊断性腹腔镜检查，但内窥镜超声和PET扫描很少进行。cT3类型最常见（40.6%），淋巴结累及占48.9%，远处转移占14.4%。最终cTNM分期为III期（29.4%）、II期（26%）、I期（24.2%）和IV期（20.5%）。大多数患者接受手术的目的是治愈（74.4%）和开放获取（82.8%）。术前化疗占37.2%，最常见的手术方式是胃大部切除术（45.3%）和全胃切除术（33.1%）。结论：本研究使我们能够评估目前胃癌手术治疗的全景，代表巴西所有地区。III期、远端和弥漫性肿瘤在巴西仍然普遍存在，因此相关的诊断性腹腔镜检查、术前化疗和微创手术已经得到应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Revista do Colegio Brasileiro de Cirurgioes Medicine-Surgery

CiteScore

1.70

自引率

0.00%

发文量

期刊介绍： History: The publication and dissemination of scientific activities of its members is one of the aims of medical societies. The Brazilian College of Surgeons (Colégio Brasileiro de Cirurgiões – CBC), founded in 1929, already in its first statute provided for the issuance of the “Bulletin of the Brazilian College of Surgeons” as its official division, whose starting number was published in January 1930. In 1967, the National Directory of CBC changed its name to "Journal of the Brazilian College of surgeons", which, however, went on to be published without due regularity. From 1974 on, the journal began to be published bi-monthly, on a regular basis, to the present day. In these more than 40 years of uninterrupted publication, the Journal of the CBC gained importance and scope. With standards and criteria for selection and publication of scientific articles in the area of General and specialist Surgery, including "peer review", the Journal of the CBC falls along the lines of the main international journals and has an Editorial Board that evaluates the merits for publication of submitted manuscripts.