Clinical case series: Spontaneous coronary artery dissection with thrombosis among young individuals with high lipoprotein(a)

IF 4.6 3区医学 Q2 PHARMACOLOGY & PHARMACY

Journal of clinical lipidology Pub Date : 2025-07-01 DOI:10.1016/j.jacl.2025.04.187

Agnes Koczo MD, Brent Medoff, Josh E. Levenson MD, Anum Saeed MD

引用次数: 0

Abstract

Young individuals who present with acute coronary syndrome (ACS) are often devoid of typical traditional atherosclerotic risk factors. As such, they pose challenges to risk stratify for diagnostic imaging and for pathogenetic etiology. We describe 2 patients who presented with ACS and found to have spontaneous coronary artery dissection with thrombosis without significant atherosclerotic burden, but high lipoprotein(a) levels.

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临床病例系列：年轻高脂蛋白患者自发性冠状动脉剥离伴血栓形成(a)。

患有急性冠脉综合征（ACS）的年轻人通常缺乏典型的传统动脉粥样硬化危险因素。因此，它们对诊断成像和病理病因学的风险分层提出了挑战。我们描述了2例ACS患者，发现自发性冠状动脉剥离伴血栓形成，没有明显的动脉粥样硬化负担，但脂蛋白(a)水平高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of clinical lipidology 医学-药学

CiteScore

7.00

自引率

6.80%

发文量

209

审稿时长

49 days

期刊介绍： Because the scope of clinical lipidology is broad, the topics addressed by the Journal are equally diverse. Typical articles explore lipidology as it is practiced in the treatment setting, recent developments in pharmacological research, reports of treatment and trials, case studies, the impact of lifestyle modification, and similar academic material of interest to the practitioner. Sections of Journal of clinical lipidology will address pioneering studies and the clinicians who conduct them, case studies, ethical standards and conduct, professional guidance such as ATP and NCEP, editorial commentary, letters from readers, National Lipid Association (NLA) news and upcoming event information, as well as abstracts from the NLA annual scientific sessions and the scientific forums held by its chapters, when appropriate.