The impact COVID-19 pandemic on coverage and inequalities in childhood immunization in Peru.

IF 4.5 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Larissa A N Silva, Francine S Costa, Bianca O Cata-Preta, Luis Huicho, Claudio F Lanata, Maria Ana Mendoza Araujo, Theresa J Ochoa, Tewodaj Mengistu, Dan Hogan, Aluisio J D Barros, Cesar G Victora
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引用次数: 0

Abstract

Background: We examined the impact of COVID-19 on childhood immunization coverage and inequalities in Peru, focusing on pentavalent, rotavirus, and pneumococcal (PCV) vaccines. Since the 1990s, Peru has worked to improve childhood vaccine coverage, but the COVID-19 pandemic posed significant challenges to the health system.

Methods: We analysed data from nationally representative health surveys conducted annually between 2015 and 2023. The surveys measured vaccine coverage among children aged 18-29 months, namely three doses for pentavalent and PCV and two doses for the rotavirus vaccine, based on data from home-based records. We studied inequalities at the individual child level using the slope index of inequality (SII) based on household wealth quintiles.

Results: In 2019, the home-based record coverage levels for pentavalent, PCV and rotavirus vaccines were 78.0%, 74.5%, and 75.9%, respectively. In 2020, these rates dropped significantly due to pandemic disruptions: PCV and pentavalent coverage fell by 14% points, and rotavirus by 12 points. By 2021, coverage levels improved, returning to pre-pandemic rates by 2022 and 2023. Individual-level analyses showed that pro-rich inequalities were present during the full study period, but these increased sharply during the pandemic in 2020, with poorer children experiencing more significant drops in coverage than wealthier children. This trend reversed by 2021 and 2022 when inequality measures returned to pre-pandemic levels. Due to reasons that are still unclear, inequality increased again in 2023. Nevertheless, the confidence intervals for the summary inequality measures are wide and must be interpreted cautiously.

Conclusions: The COVID-19 pandemic temporarily disrupted Peru's childhood immunization efforts, particularly affecting poorer populations, but coverage rebounded to pre-pandemic levels by 2022. These findings contribute to the scant literature on the pandemic's impact on vaccine equity.

COVID-19大流行对秘鲁儿童免疫接种覆盖率和不平等现象的影响。
背景:我们研究了COVID-19对秘鲁儿童免疫覆盖率和不平等的影响,重点关注五价、轮状病毒和肺炎球菌(PCV)疫苗。自20世纪90年代以来,秘鲁一直致力于提高儿童疫苗覆盖率,但COVID-19大流行给卫生系统带来了重大挑战。方法:我们分析了2015年至2023年间每年进行的具有全国代表性的健康调查数据。根据来自家庭记录的数据,这些调查测量了18-29个月儿童的疫苗覆盖率,即五价和PCV疫苗接种三剂,轮状病毒疫苗接种两剂。我们使用基于家庭财富五分位数的不平等斜率指数(SII)研究了个体儿童水平上的不平等。结果:2019年,五价、PCV和轮状病毒疫苗的家庭记录覆盖率分别为78.0%、74.5%和75.9%。2020年,由于大流行的中断,这些比率大幅下降:PCV和五价病毒覆盖率下降了14%,轮状病毒覆盖率下降了12%。到2021年,覆盖率有所提高,到2022年和2023年恢复到大流行前的水平。个人层面的分析表明,在整个研究期间都存在有利于富人的不平等现象,但在2020年大流行期间,这种不平等现象急剧加剧,贫困儿童的覆盖率下降幅度大于富裕儿童。到2021年和2022年,不平等衡量指标恢复到大流行前的水平,这一趋势发生逆转。由于尚不清楚的原因,不平等在2023年再次加剧。然而,总结性不平等测度的置信区间很宽,必须谨慎解释。结论:2019冠状病毒病大流行暂时扰乱了秘鲁的儿童免疫接种工作,特别是对贫困人口的影响,但到2022年,覆盖率回升至大流行前的水平。这些发现有助于弥补关于大流行对疫苗公平影响的文献不足。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
7.80
自引率
4.20%
发文量
162
审稿时长
28 weeks
期刊介绍: International Journal for Equity in Health is an Open Access, peer-reviewed, online journal presenting evidence relevant to the search for, and attainment of, equity in health across and within countries. International Journal for Equity in Health aims to improve the understanding of issues that influence the health of populations. This includes the discussion of political, policy-related, economic, social and health services-related influences, particularly with regard to systematic differences in distributions of one or more aspects of health in population groups defined demographically, geographically, or socially.
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