Differences in timeliness, completeness and drop-out rates of MMRV and DTP containing vaccines among Ultra-Orthodox Jews and others in a deprived Northern Israel city: an ecological study.

IF 4.5 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Avraham Jacobson, Sivan Spitzer, Michael Edelstein
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引用次数: 0

Abstract

Background: The Ultra-Orthodox Jewish (UO) population has been affected by pertussis, polio, and measles outbreaks. Safed, a deprived, undervaccinated city in Israel's North, has a large UO population concentrated in specific neighborhoods. We determined whether in Safed UO population concentration was associated with DTP- containing and MMRV1 vaccines coverage, timeliness and drop-out rates.

Method: For each of Safed's statistical areas, we estimated UO population based on the proportion of votes for UO political parties in Israel's 2020 general elections. We determined whether this proportion was associated with timely and delayed MMRV1 and DTP vaccine coverage for children born 2017-2022 using simple linear regression. We compared DTP and MMRV1 coverage and drop-out rates in UO areas (> 50% vote for UO parties) to others, using chi-square tests.

Results: All eligible 4385 children residing in Safed were included in the MMRV1 and DTP analyses. Vaccine coverage was significantly lower in UO areas compared to non-UO for all doses of DTP and MMRV1 at expected age (-11.8, -15.8, -16.6, -11.8 and - 7.1% points (pp) respectively, P < 0.005) - and at 36 months old (-0.5, -3.9, -6.2, -9.3 and - 2% points respectively, P < 0.005). Gaps narrowed more for MMRV1 (from 7.1 to2 pp), than for DTP4 (from 11.8 to9.3 pp). Increasing UO vote was associated with decreased timely coverage for DTP but not MMRV. DTP1-4 drop-out rates were larger in the UO areas than in non-UO areas (26.2% vs. 18%).

Conclusions: Vaccine coverage was lower in UO neighborhoods, even in a peripheral city where coverage in non-UO areas is already low. Coverage differences between UO and non-UO populations decreased with time for MMRV1 but not DTP. Our findings suggest timeliness should be considered alongside non-vaccination, and vaccination behavior may be vaccine-specific in the UO population.

在以色列北部一个贫困城市的极端正统派犹太人和其他人之间,含有MMRV和百白破疫苗的及时性、完整性和辍学率的差异:一项生态学研究。
背景:极端正统派犹太人(UO)人口受到百日咳、脊髓灰质炎和麻疹暴发的影响。萨法德是以色列北部一个贫困、疫苗接种不足的城市,有大量的乌乌组织人口集中在特定的社区。我们确定在安全的UO人口浓度是否与百白破和MMRV1疫苗的覆盖率、及时性和退出率相关。方法:对于Safed的每个统计区域,我们根据以色列2020年大选中UO政党的选票比例估计UO人口。我们使用简单线性回归确定这一比例是否与2017-2022年出生的儿童及时和延迟的MMRV1和百白破疫苗覆盖率相关。我们使用卡方检验比较了DTP和MMRV1在UO地区的覆盖率和退选率(大约50%的人投票给UO政党)。结果:所有符合条件的4385名居住在Safed的儿童被纳入MMRV1和DTP分析。在预期年龄,UO地区的百白破和MMRV1的所有剂量的疫苗覆盖率明显低于非UO地区(分别为-11.8,-15.8,-16.6,-11.8和- 7.1%点(pp))。结论:UO社区的疫苗覆盖率较低,即使在非UO地区覆盖率已经很低的外围城市也是如此。在MMRV1和DTP中,UO和非UO人群的覆盖率差异随时间而减小,而DTP没有。我们的研究结果表明,除了未接种疫苗外,还应考虑及时性,并且在UO人群中,疫苗接种行为可能是疫苗特异性的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
7.80
自引率
4.20%
发文量
162
审稿时长
28 weeks
期刊介绍: International Journal for Equity in Health is an Open Access, peer-reviewed, online journal presenting evidence relevant to the search for, and attainment of, equity in health across and within countries. International Journal for Equity in Health aims to improve the understanding of issues that influence the health of populations. This includes the discussion of political, policy-related, economic, social and health services-related influences, particularly with regard to systematic differences in distributions of one or more aspects of health in population groups defined demographically, geographically, or socially.
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