Filip Ivanovski, Vid Jazbec, Nina Varda, Roman Jerala, Mojca Beneina
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引用次数: 0
Abstract
Sonogenetics is developing into a powerful tool in synthetic biology. The coupling of ultrasound with genetically engineered effectors enables non-invasive and precise control of cellular and molecular processes. Building on established techniques such as optogenetics, it overcomes the limits of tissue penetration and invasiveness, making it a promising tool for both research and therapeutic applications. Recent advances in acoustic contrast agents, such as microbubbles and gas vesicles, have improved the mechanical effects of ultrasound on cells, extending its application to various biological systems. This review highlights recent advances and challenges, such as standardization of parameters and understanding of underlying mechanisms, and outlines future directions for ultrasound-guided cellular control.
期刊介绍：
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control includes the theory, technology, materials, and applications relating to: (1) the generation, transmission, and detection of ultrasonic waves and related phenomena; (2) medical ultrasound, including hyperthermia, bioeffects, tissue characterization and imaging; (3) ferroelectric, piezoelectric, and piezomagnetic materials, including crystals, polycrystalline solids, films, polymers, and composites; (4) frequency control, timing and time distribution, including crystal oscillators and other means of classical frequency control, and atomic, molecular and laser frequency control standards. Areas of interest range from fundamental studies to the design and/or applications of devices and systems.
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