Bone marrow aspirate concentrate adjunct for acetabular labral tear repair: a systematic review and meta-analysis.

IF 1.3 4区医学 Q3 ORTHOPEDICS

HIP International Pub Date : 2025-05-15 DOI:10.1177/11207000251337403

Seth Spicer, Hanna Brancaccio, Ashley Sundin, Jamie Bono, John DesRochers, Brandon Goodwin, Nicholas Averell, Seungkyu Park, Alexandra Goodwin, William DiCiurcio, Richard Jermyn

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引用次数: 0

Abstract

Background: The objective of this study was to determine the effect of bone marrow aspirate concentrate (BMAC) on long-term patient outcomes when used as an adjuvant to acetabular repair of the labrum.

Methods: A systematic review and meta-analysis were completed following PRISMA 2020 guidelines. Included in the analysis were controlled studies which assessed functional outcomes via the International Hip Outcome Tool-33 (iHOT-33) 12 or 24 months after acetabular repair with BMAC adjunct. Four studies totaling 315 participants were analysed.

Results: Pooled effect sizes for iHOT-33 scores were not significantly different between control and treatment groups at 12 (p = 0.14, Cohen's D ≏ 0.79) or 24 months (p = 0.30, Cohen's D ≏ 0.56).

Conclusions: Non-significant trends in favor of BMAC augmentation were found in this study. However, the trends reported are promising and warrant further investigation with further randomised controlled trials.

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骨髓浓缩液用于髋臼唇撕裂修复：一项系统回顾和荟萃分析。

背景：本研究的目的是确定骨髓浓缩液（BMAC）作为辅助髋臼唇修复时对患者长期预后的影响。方法：遵循PRISMA 2020指南完成系统评价和荟萃分析。分析纳入对照研究，通过国际髋关节预后工具-33 （iHOT-33）评估BMAC辅助髋臼修复术后12或24个月的功能结果。共分析了四项研究，共计315名参与者。结果：iHOT-33评分在12个月（p = 0.14, Cohen's D≏0.79）或24个月（p = 0.30, Cohen's D≏0.56）时，对照组和治疗组的合并效应量无显著差异。结论：在本研究中发现了有利于BMAC增强的非显著趋势。然而，报告的趋势是有希望的，值得进一步的随机对照试验进行调查。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

HIP International 医学-整形外科

CiteScore

4.20

自引率

0.00%

发文量

审稿时长

2 months

期刊介绍： HIP International is the official journal of the European Hip Society. It is the only international, peer-reviewed, bi-monthly journal dedicated to diseases of the hip. HIP International considers contributions relating to hip surgery, traumatology of the hip, prosthetic surgery, biomechanics, and basic sciences relating to the hip. HIP International invites reviews from leading specialists with the aim of informing its readers of current evidence-based best practice. The journal also publishes supplements containing proceedings of symposia, special meetings or articles of special educational merit. HIP International is divided into six independent sections led by editors of the highest scientific merit. These sections are: • Biomaterials • Biomechanics • Conservative Hip Surgery • Paediatrics • Primary and Revision Hip Arthroplasty • Traumatology